9 completed, 1 enrolling by invitation. 3 Phase 1, 3 Phase 3, 2 Phase 2, 1 Early Phase 1, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 2 |
| Early Phase 1 | 1 | Completed 1 |
| Not applicable | 1 | Enrolling by invitation 1 |
Follow Nonoxynol: new trials by email Literature Review of Nonoxynol trials Research Report on Nonoxynol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AI-Augmented Diagnostic Assessment With ENLIGHT Versus Independent Pathologist Review Unaided Review First, Then AI as Double-Check, Then AI as First-Look., Unaided Review First, Then AI as First-Look, Then AI as Double-Check., AI as Double-Check First, Then AI as First-Look, Then Unaided Review. - Cancer | Not applicable | Enrolling by invitation | Harvard Medical School (HMS and HSDM) | 25 | 2026-07-01 | 2026-08-03 |
| Effect of Concomitant Use of an Antimycotic, an Antibiotic, a Spermicide or Tampons on Pharmacokinetics of Anastrozole and Levonorgestrel Released From Intra-vaginal Ring Anastrozole / Levonorgestrel (BAY98-7196), Gyno-Daktarin, Sobelin vaginal creme - Endometriosis | Phase 1 | Completed | Bayer | 52 | 2015-09-15 | 2017-07-24 |
| Postcoital Testing Study of the SILCS Diaphragm Used With 3% N-9 Gel, ContraGel, or No Gel SILCS diaphragm used with ContraGel, SILCS diaphragm used with 3% Nonoxynol-9, SILCS diaphragm - Contraception | Phase 1 | Completed | CONRAD | 27 | 2014-12-01 | 2016-08-01 |
| Identification of Novel Biomarkers of Cervicovaginal Mucosal Inflammation Imiquimod, Placebo, Nonoxynol-9 - Vaginal Inflammation, Vaginal Infections | Phase 2 | Completed | CONRAD | 20 | 2012-05-01 | 2015-03-31 |
| Study of Contraceptive Efficacy & Safety of Phexxi™ (Previously Known as Amphora) Gel Compared to Conceptrol Vaginal Gel Conceptrol, Amphora - Contraception | Phase 3 | Completed | Evofem Inc. | 3389 | 2011-04-01 | 2022-07-12 |
| A Pilot Study for Toxicity Evaluation of HIV Rectal Microbicides Normosol-R, Nonoxynol-9, Gastrointestinal instrumentation - HIV Infections | Early Phase 1 | Completed | Johns Hopkins University | 12 | 2007-04-01 | 2015-04-01 |
| Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol® C31G, nonoxynol-9 (N-9) - Pregnancy | Phase 3 | Completed | Premier Research | 1565 | 2004-06-01 | 2018-05-01 |
| Effectiveness of BenZalkonium Chloride Gel as Vaginal Contraceptive: a Multicentric Randomized Controlled Trial a novel Benzalkonium Chloride (BZK) contraceptive gel, LELEMI® contraceptive gel containing 50mg nonoxynol-9 - Healthy | Phase 2 | Completed | Shanghai Institute of Planned Parenthood Research | 240 | 2004-03-01 | 2009-07-10 |
| A Study of Nonoxynol-9 (N-9) and HIV Infection Nonoxynol-9 - HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 4400 | 2021-10-29 | |
| A Study of the Effects of Advantage 24 on the Rectum Nonoxynol-9 - HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 70 | 2021-10-29 |
HIV Infections (3) · Endometriosis (1) · Homosexuality, Male (1) · Neoplasms (1) · Patient Compliance (1) · Vaginitis (1)
CONRAD (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Bayer (1) · Evofem Inc. (1) · Harvard Medical School (HMS and HSDM) (1) · Johns Hopkins University (1) · Premier Research (1) · Shanghai Institute of Planned Parenthood Research (1)
United States (8) · China (1) · Dominican Republic (1) · Germany (1) · Russia (1)
Andrea R Thurman, MD (1) · Connie Celum (1) · Diana L Blithe, Ph.D. (1) · Edward Fuchs, PA-C, MBA (1) · Jinxun XU, MD (1) · Kelly Culwell, MD (1) · Nancy Padian (1) · Susan Buchbinder (1) · Taha E.Taha (1)
PMID 16773032, PMID 21099590, PMID 23325915
2014 (1)