MK-8776: Clinical Trials

3 trials of MK-8776, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

2 completed, 1 terminated. 2 Phase 1, 1 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 12Completed 1, Terminated 1
Phase 21Completed 1

Follow MK-8776: new trials by email Literature Review of MK-8776 trials Research Report on MK-8776

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Cytarabine With or Without SCH 900776 in Treating Adult Patients With Relapsed Acute Myeloid Leukemia
Cytarabine, CHK1 Inhibitor SCH 900776, Laboratory Biomarker Analysis - Adult Acute Megakaryoblastic Leukemia, Adult Acute Monoblastic Leukemia
Phase 2CompletedNational Cancer Institute (NCI)322013-05-012016-09-01
Study of SCH 900776 (MK-8776) With and Without Cytarabine in Participants With Acute Leukemias (P05247)
MK-8776, Cytarabine - Myelogenous Leukemia, Acute, Leukemia, Lymphocytic, Acute
Phase 1TerminatedMerck Sharp & Dohme LLC242009-07-292018-08-27
A Dose-escalation Study of MK-8776 (SCH 900776) With and Without Gemcitabine in Participants With Solid Tumors or Lymphoma (MK-8776-002/P05248)
MK-8776, Gemcitabine - Hodgkin Disease, Lymphoma, Non-Hodgkin
Phase 1CompletedMerck Sharp & Dohme LLC452008-10-172018-08-27

Conditions studied

Leukemia, Myeloid, Acute (2)  ·  Hodgkin Disease (1)  ·  Leukemia, Erythroblastic, Acute (1)  ·  Leukemia, Megakaryoblastic, Acute (1)  ·  Leukemia, Monocytic, Acute (1)  ·  Leukemia, Myeloid, Accelerated Phase (1)  ·  Leukemia, Myelomonocytic, Acute (1)  ·  Lymphoma, Non-Hodgkin (1)  ·  Neoplasms (1)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)

Sponsors

Merck Sharp & Dohme LLC (2)  ·  National Cancer Institute (NCI) (1)

Countries

United States (1)

Top investigators

B. Smith (1)

Results publications

PMID 23092873

NIH funding

P30CA006973 (1), U01CA070095 (1)