7 completed, 4 active not recruiting, 4 recruiting, 2 unknown. 9 Not applicable, 2 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 4, Active not recruiting 2, Unknown 2, Recruiting 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Mastectomy, Subcutaneous: new trials by email Literature Review of Mastectomy, Subcutaneous trials Research Report on Mastectomy, Subcutaneous
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Single-Stage Prepectoral Placement of Textured Implants Using a Polyester Mesh Endoprostheses With Fluoropolymer Coating in Patients With Breast Cancer Subcutaneous mastectomy using a fluoropolymer-coated polyester mesh endoprosthesis with simultaneous prepectoral placement of textured implants., Subcutaneous mastectomy with simultaneous prepectoral placement of textured implants. - Breast Cancer, Breast Reconstruction | Not applicable | Active not recruiting | Saint Petersburg State University, Russia | 100 | 2025-05-15 | 2025-09-22 |
| Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer Nipple Sparing Mastectomy (NSM), Skin-Sparing Mastectomy (SSM), Total (Simple) Mastectomy - Breast Cancer Surgery | Recruiting | Sir Mortimer B. Davis - Jewish General Hospital | 4700 | 2025-02-01 | 2026-08-18 | |
| Feasibility and Acceptability of Endoscopic Mastectomy in Patients With Breast Cancer Nipple-Sparing Mastectomy, with immediate breast reconstruction - Breast Cancer | Not applicable | Recruiting | University Hospital, Montpellier | 20 | 2024-10-18 | 2026-01-05 |
| Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and Reconstruction Neurotization Procedure, Questionnaire Administration, Subcutaneous Mastectomy - Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | Phase 2 | Recruiting | Mayo Clinic | 45 | 2023-12-05 | 2026-10-02 |
| Evaluation of Feasibility and Aesthetic Outcomes of Benelli Technique for Nipple Sparing Mastectomy in Surgical Treatment of Grade 3 and 4 Gynecomastia Benelli technique for nipple sparing mastectomy in surgical treatment of grade 3 and 4 gynecomastia - Surgical Managment of Gynecomastia | Not applicable | Unknown | Assiut University | 30 | 2023-05-19 | 2024-06-25 |
| Post Market Clinical Follow-up Study on da Vinci® Robotic-assisted Prophylactic Nipple Sparing Mastectomy With Breast Reconstruction Nipple-Sparing Mastectomy - Prophylactic Nipple Sparing Mastectomy (NSM) | Terminated | Intuitive Surgical | 7 | 2022-01-18 | 2023-12-22 | |
| Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy Nipple-Sparing Mastectomy - Nipple Sparing Mastectomy | Not applicable | Active not recruiting | Intuitive Surgical | 145 | 2021-03-26 | 2025-12-18 |
| ESM Versus OM ：A Randomized Controlled Trial subcutaneous mastectomy, endoscopic subcutaneous mastectomy - Endoscopic Subcutaneous Mastectomy | Not applicable | Unknown | Beijing Friendship Hospital | 287 | 2020-12-01 | 2020-12-01 |
| Open Nipple Sparing Mastectomy (NSM) Nipple Sparing Mastectomy - Nipple Sparing Mastectomy | Active not recruiting | Intuitive Surgical | 75 | 2020-09-21 | 2026-03-24 | |
| Prospective Study of MAstectomy With Reconstruction Including Robot Endoscopic Surgery Robotic or endoscopic nipple sparing mastectomy, Conventional mastectomy (including nipple sparing mastectomy, skin sparing mastectomy) - Breast Neoplasms, Germline BRCA1 Gene Mutation | Active not recruiting | Severance Hospital | 2000 | 2020-04-08 | 2025-05-15 | |
| Outcomes of a Novel Technique Minimal Scar Mastectomy nipple sparing mastectomy without reconstruction - Breast Cancer Early Stage Breast Cancer (Stage 1-3) | Recruiting | KK Women's and Children's Hospital | 100 | 2017-03-01 | 2024-11-06 | |
| Compare Outcomes Between Two Acellular Dermal Matrices Alloderm RTU, Cortiva 1mm Allograft Dermis, Skin or nipple-sparing mastectomy - Breast Cancer | Phase 2 | Completed | Washington University School of Medicine | 320 | 2017-01-31 | 2023-05-06 |
| Assessment of Nipple Sparing Mastectomy as a Treatment Option for Breast Cancer nipple sparing mastectomy - Breast Cancer | Completed | Alexandria University | 35 | 2017-01-01 | 2020-11-23 | |
| SKINI - Radicality of Skin-Sparing and Nipple-Sparing Mastectomy Skin-Sparing Mastectomy (SSM), Nipple-Sparing Mastectomy (NSM) - Surgery | Not applicable | Completed | Brust-Zentrum AG | 160 | 2016-04-12 | 2018-03-21 |
| Therapeutic Nipple Sparing Mastectomy. Nipple sparing mastectomy - Breast Cancer | Phase 3 | Completed | Institut Claudius Regaud | 450 | 2015-02-09 | 2026-04-14 |
| Breast Reconstruction With Acellular Dermal Matrix in the Setting of Breast Cancer Treatment Reconstruction with ADM., Skin or nipple sparing mastectomy, Reconstruction with implant - Breast Cancer | Not applicable | Completed | Karolinska University Hospital | 135 | 2014-04-01 | 2018-04-24 |
| Nipple-Areola Complex (NAC) Irradiation After Nipple-Sparing Mastectomy and Reconstruction Nipple-Sparing Mastectomy, Breast Reconstruction, Axillary Surgery - Breast Cancer, Ductal Carcinoma | Not applicable | Completed | University of Miami | 21 | 2010-03-16 | 2026-08-13 |
| Nipple Sparing Mastectomy - Cosmetic Outcomes Nipple Sparing Mastectomy - Breast Cancer, Breast Reconstruction | Not applicable | Completed | Wake Forest University Health Sciences | 75 | 2009-01-21 | 2022-04-21 |
Breast Neoplasms (10) · Breast Carcinoma In Situ (1) · Carcinoma in Situ (1) · Carcinoma, Ductal (1) · Cystic Fibrosis (1) · Hamartoma Syndrome, Multiple (1) · Li-Fraumeni Syndrome (1)
Intuitive Surgical (3) · Alexandria University (1) · Assiut University (1) · Beijing Friendship Hospital (1) · Brust-Zentrum AG (1) · Institut Claudius Regaud (1) · KK Women's and Children's Hospital (1) · Karolinska University Hospital (1) · Mayo Clinic (1) · Saint Petersburg State University, Russia (1) · Severance Hospital (1) · Sir Mortimer B. Davis - Jewish General Hospital (1) · University Hospital, Montpellier (1) · University of Miami (1) · Wake Forest University Health Sciences (1)
United States (7) · France (3) · Egypt (2) · South Korea (2) · United Kingdom (2) · Australia (1) · Belgium (1) · Canada (1) · China (1) · Italy (1) · Japan (1) · Portugal (1) · Russia (1) · Singapore (1) · Sweden (1)
Antonio Toesca, MD (1) · Benjamin Sarfati, MD (1) · Cristiane Takita, MD (1) · Fredrik Lohmander, MD (1) · Hyung Seok Park, MD, PhD (1) · James W. Jakub, M.D. (1) · Olivia S. Ho, M.D., M.S. (1) · Richard L White, MD (1) · Terence M Myckatyn, M.D. (1)
PMID 10456706, PMID 2185619, PMID 30830538, PMID 3087145, PMID 31113185, PMID 32762012, PMID 34596671, PMID 35501091
2016 (1)