5 completed. 5 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
| Phase 2 | 1 | Completed 1 |
Follow Malarone: new trials by email Literature Review of Malarone trials Research Report on Malarone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Atoguanil BA Study Atoguanil, Malarone - Bioavailability | Phase 1 | Completed | Medicines for Malaria Venture | 16 | 2021-11-17 | 2022-05-05 |
| Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteers Atovaquone / Proguanil 250/100 mg, Tegoprazan 50 mg, Esomeprazole 40 mg - Gastroesophageal Reflux Disease | Phase 1 | Completed | Seoul National University Hospital | 19 | 2020-11-25 | 2021-09-27 |
| Safety and Protective Efficacy of IV Immunization With Cryopreserved PfSPZ Under A/P Chemoprophylaxis atovaquone/proguanil 250mg/100mg (A/P), PfSPZ Challenge (NF54), NaCl 0,9% - Malaria | Phase 1 | Completed | University Hospital Tuebingen | 30 | 2016-11-28 | 2019-07-15 |
| Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1 Sulfadoxine-pyrimethamine (low dose), Piperaquine (low dose), Sulfadoxine-pyrimethamine (high dose) - Malaria | Phase 1 / Phase 2 | Completed | Radboud University Medical Center | 29 | 2016-06-01 | 2018-03-23 |
| DSM265 Chemoprophylaxis of Plasmodium Falciparum Malaria DSM265 400mg, Placebo to DSM265 400 mg, Plasmodium falciparum sporozoite challenge - Plasmodium Falciparum, Malaria | Phase 1 | Completed | Medicines for Malaria Venture | 22 | 2015-10-01 | 2021-01-13 |
Malaria (4) · Gastroesophageal Reflux (1) · Malaria, Falciparum (1)
Medicines for Malaria Venture (2) · Radboud University Medical Center (1) · Seoul National University Hospital (1) · University Hospital Tuebingen (1)
Germany (1) · Netherlands (1) · South Korea (1) · United Kingdom (1)
Peter G Kremsner, Prof (1) · SeungHwan Lee, MD, PhD (1) · Ulrike Lorch, MD FRCA FFPM (1)
PMID 28363637, PMID 29482720, PMID 31146732, PMID 36897544, PMID 38918235