3 completed, 2 terminated. 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 3, Terminated 2 |
Follow lorecivivint: new trials by email Literature Review of lorecivivint trials Research Report on lorecivivint
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Knee Osteoarthritis (STRIDES) Lorecivivint, Placebo - Knee Osteoarthritis | Phase 3 | Completed | Biosplice Therapeutics, Inc. | 499 | 2022-11-18 | 2026-09-01 |
| 3-year, Open-Label Study Evaluating Safety, Tolerability, and Efficacy of Lorecivivint in Knee Osteoarthritis Lorecivivint - Osteoarthritis of the Knee | Phase 3 | Terminated | Biosplice Therapeutics, Inc. | 72 | 2021-07-15 | 2026-03-31 |
| A Long-Term Safety and Efficacy Study of Lorecivivint in Subjects With Osteoarthritis of the Knee Placebo, Lorecivivint - Osteoarthritis, Knee | Phase 3 | Terminated | Biosplice Therapeutics, Inc. | 276 | 2020-08-25 | 2026-03-24 |
| Patient-Reported Outcomes in Evaluating Lorecivivint (SM04690) for Moderate to Severe Knee Osteoarthritis (STRIDES-1) Lorecivivint, Placebo - Knee Osteoarthritis | Phase 3 | Completed | Biosplice Therapeutics, Inc. | 496 | 2020-05-26 | 2026-02-04 |
| Patient-Reported and Radiographic Outcomes in Evaluating Lorecivivint (SM04690) for the Treatment of Knee Osteoarthritis Lorecivivint, Placebo - Knee Osteoarthritis | Phase 3 | Completed | Biosplice Therapeutics, Inc. | 501 | 2019-05-17 | 2026-02-13 |
Osteoarthritis, Knee (5) · Osteoarthritis (4)
Biosplice Therapeutics, Inc. (5)
United States (5)
Yusuf Yazici, M.D. (2) · Yusuf Yazici, MD (2) · Ismail Simsek, MD (1)