2 completed, 2 unknown, 1 terminated. 3 Phase 3, 1 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 2, Unknown 1 |
| Not applicable | 1 | Unknown 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Loop diuretics: new trials by email Literature Review of Loop diuretics trials Research Report on Loop diuretics
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dapagliflozin in Reducing Epicardial Adipose Tissue in Heart Failure with Preserved Ejection Fraction Dapagliflozin 10 mg once daily, Loop diuretics, Treatments of associated co-morbidities (e.g Anti-hypertensive, oral hypoglycemic) - Heart Failure with Preserved Ejection Fraction | Not applicable | Unknown | Aswan University | 70 | 2024-08-01 | 2024-07-19 |
| Sequential Nephron Blockade in Acute Heart Failure Metolazone, Loop Diuretics - Acute Heart Failure | Phase 3 | Unknown | Policlinico Casilino ASL RMB | 310 | 2019-10-01 | 2019-11-19 |
| Nitroglycerin vs. Furosemide Using Lung Ultrasound Pilot Trial Nitrates, Loop Diuretics - Heart Failure, Heart Failure Acute | Phase 2 | Terminated | Indiana University | 52 | 2017-12-14 | 2024-08-20 |
| Diuretic Response in Advanced Heart Failure: Bolus Intermittent vs Continuous INfusion Loop Diuretics - Heart Failure NYHA Class III, Heart Failure NYHA Class IV | Phase 3 | Completed | University of Turin, Italy | 80 | 2013-05-01 | 2018-07-19 |
| Determining Optimal Dose and Duration of Diuretic Treatment in People With Acute Heart Failure (The DOSE-AHF Study) Furosemide-Q12 hour bolus, Furosemide-Continuous Infusion, Furosemide-Low Intensification - Heart Failure | Phase 3 | Completed | Duke University | 308 | 2008-02-01 | 2018-03-06 |
Heart Failure (2) · Edema (1) · Pulmonary Edema (1)
Aswan University (1) · Duke University (1) · Indiana University (1) · Policlinico Casilino ASL RMB (1) · University of Turin, Italy (1)
Italy (2) · United States (2) · Canada (1)
Eugene Braunwald, MD (1) · Gennaro Cice, MD (1) · Kerry L. Lee, PhD (1) · Peter S Pang, MD (1) · Simone Frea, MD (1)
PMID 21366472, PMID 23194486, PMID 23250981, PMID 25543972, PMID 26041600, PMID 26927285, PMID 27514750, PMID 31256261, PMID 38775253, PMID 42021144
U01HL084904 (1)