4 completed, 1 active not recruiting, 1 available, 1 not yet recruiting. 3 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 3 | Active not recruiting 1, Completed 1, Not yet recruiting 1 |
Follow Linerixibat: new trials by email Literature Review of Linerixibat trials Research Report on Linerixibat
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| J-LINX: Japan LINerixibat eXtension Study Linerixibat - Pruritus | Phase 3 | Not yet recruiting | GlaxoSmithKline | 40 | 2026-10-09 | 2026-10-06 |
| Food Effect Study of Linerixibat Tablets in Healthy Adult Participants linerixibat - Pruritus | Phase 1 | Completed | GlaxoSmithKline | 23 | 2022-08-11 | 2022-11-29 |
| Phase I Study of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Controls Linerixibat - Pruritus | Phase 1 | Completed | GlaxoSmithKline | 8 | 2022-07-19 | 2023-01-18 |
| Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Adult Participants Obeticholic acid, Linerixibat - Pruritus | Phase 1 | Completed | GlaxoSmithKline | 52 | 2021-11-23 | 2022-11-08 |
| Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN) Linerixibat, Placebo - Pruritus | Phase 3 | Completed | GlaxoSmithKline | 238 | 2021-08-27 | 2026-07-22 |
| Linerixibat Long-term Safety, and Tolerability Study Linerixibat - Cholestasis | Phase 3 | Active not recruiting | GlaxoSmithKline | 242 | 2020-07-14 | 2026-06-22 |
| Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC) Linerixibat - Pruritus | Available | GlaxoSmithKline | 2025-02-27 |
Pruritus (6) · Liver Cirrhosis, Biliary (5) · Cholestasis (2) · Liver Cirrhosis (1)
GlaxoSmithKline (7)
United Kingdom (3) · United States (3) · Germany (2) · Argentina (1) · Brazil (1) · Bulgaria (1) · Canada (1) · China (1) · Czechia (1) · France (1) · Israel (1) · Italy (1) · Japan (1) · Mexico (1) · Poland (1)
2019 (1)