6 completed, 1 recruiting, 1 unknown. 5 Phase 2, 2 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Recruiting 1, Unknown 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow levodopa-carbidopa: new trials by email Literature Review of levodopa-carbidopa trials Research Report on levodopa-carbidopa
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of Silymarin in Neuroprotection and Symptom Management in Parkinson's Disease levodopa-carbidopa, Silymarin - Parkinson Disease | Phase 2 | Recruiting | Tanta University | 50 | 2025-05-10 | 2025-09-10 |
| Montelukast in Parkinson Disease levodopa-carbidopa, Montelukast - Parkinson Disease | Phase 2 / Phase 3 | Completed | Mostafa Bahaa | 60 | 2023-11-05 | 2026-10-02 |
| Clinical Study to Evaluate the Possible Efficacy of Metformin in Patients With Parkinson's Disease levodopa-carbidopa, Metformin - Parkinson Disease | Phase 2 | Completed | Tanta University | 60 | 2023-01-06 | 2026-03-13 |
| Acute Effects of Pharmacological Neuromodulation on Leg Motor Activity in Patients With SCI Treated With EES Buspirone, Levodopa-Carbidopa, Buspirone + Levodopa-Carbidopa - Spinal Cord Injuries, Drug Effect | Phase 1 | Completed | Centre Hospitalier Universitaire Vaudois | 3 | 2020-09-11 | 2023-10-05 |
| Studying a Potential Protective Effect of L-Dopa on Retinitis Pigmentosa levodopa-carbidopa - Retinitis Pigmentosa | Phase 2 | Unknown | Beirut Eye Specialist Hospital | 50 | 2016-06-01 | 2016-07-19 |
| A Pharmacokinetic Study of Levodopa and Carbidopa Intestinal Gel in Subjects With Advanced Parkinson's Disease Levodopa-Carbidopa - Parkinson Disease | Phase 1 | Completed | AbbVie | 19 | 2010-04-01 | 2017-11-21 |
| Efficacy, Safety, and Pharmacokinetics/Pharmacodynamic Study of L-Dopa/Carbidopa To Treat Parkinson's Disease levodopa-carbidopa - Parkinson's Disease | Phase 2 | Completed | Osmotica Pharmaceutical US LLC | 78 | 2007-11-01 | 2009-01-14 |
| Effect of Levodopa-Carbidopa on Visual Function in Patients With Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy levodopa-carbidopa - Nonarteritic Anterior Ischemic Optic Neuropathy | Phase 4 | Completed | Shahid Beheshti University of Medical Sciences | 2002-06-01 | 2008-10-20 |
Parkinson Disease (5) · Optic Neuropathy, Ischemic (1) · Retinitis Pigmentosa (1) · Spinal Cord Injuries (1)
Tanta University (2) · AbbVie (1) · Beirut Eye Specialist Hospital (1) · Centre Hospitalier Universitaire Vaudois (1) · Mostafa Bahaa (1) · Osmotica Pharmaceutical US LLC (1) · Shahid Beheshti University of Medical Sciences (1)
Egypt (3) · Argentina (1) · Iran (1) · Lebanon (1) · Switzerland (1)
Elias F. Jarade, MD (1) · Gustavo Fischbein, M.D. (1) · Janet Benesh (1) · Jocelyne Bloch, Pr MD (1) · Mohammad Pakravan, MD (1)
2009 (1), 2019 (1)