8 completed, 3 unknown. 4 Not applicable, 3 Phase 4, 2 Phase 3, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 4 |
| Phase 4 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Early Phase 1 | 1 | Unknown 1 |
Follow Leukotriene Antagonists: new trials by email Literature Review of Leukotriene Antagonists trials Research Report on Leukotriene Antagonists
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Real-world Evaluation of the Effectiveness of Immunoglobulin-Histamine Complex, IHC (Histoglob) in Chronic Urticaria Antihistaminics, H2 blockers, Leukotriene antagonists, Immunoglobulin/Histamine Complex (IHC) Injection - Chronic Urticaria | Completed | Bharat Serums and Vaccines Limited | 660 | 2025-12-31 | 2026-10-02 | |
| Prospective Multicenter Observational Study and Promotion of the Application of Focused Ultrasound in Allergic Rhinitis High-intensity focused ultrasound (HIFU), intranasal corticosteroids, oral antihistamines, oral leukotriene receptor antagonists, and intranasal antihistamines - Allergic Rhinitis | Early Phase 1 | Unknown | Chongqing Medical University | 240 | 2023-08-01 | 2024-02-22 |
| The Efficacy of Leukotriene Inhibitor in Adult Patients With Moderate SARS-COV-2 Symptoms (COVID19) Leukotriene Receptor Antagonist, Placebo - Moderate Covid19 | Phase 3 | Unknown | King Abdullah International Medical Research Center | 66 | 2021-02-28 | 2021-05-10 |
| Experienced Chinese Herbal Formulas on Pediatric Asthma experienced chinese herbal formulas, leukotriene receptor antagonist and bronchial relaxant - Childhood Asthma | Not applicable | Completed | Children's Hospital of Fudan University | 182 | 2013-03-01 | 2015-08-11 |
| Role of Leukotriene Receptor Antagonists in Treatment of Chronic Periodontitis Montelukast, Placebo - Chronic Periodontitis | Phase 4 | Completed | Tatyasaheb Kore Dental College | 60 | 2012-03-01 | 2013-12-19 |
| A Safety Study of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU) Who Remain Symptomatic Despite Treatment With H1 Antihistamines, H2 Blockers, and/or Leukotriene Receptor Antagonists Omalizumab, Placebo, H1 antihistamine, H2 antihistamine, leukotriene receptor antagonist - Chronic Idiopathic Urticaria | Phase 3 | Completed | Genentech, Inc. | 336 | 2011-02-01 | 2013-11-26 |
| Leukotriene D4 Bronchial Provocation Test (LTD4-BPT) as an Indicator for the Use of Leukotriene Receptor Antagonist (LTRA) leukotriene receptor antagonist (montelukast) - Bronchial Asthma | Not applicable | Completed | Guangzhou Institute of Respiratory Disease | 32 | 2010-03-01 | 2011-08-18 |
| Montelukast in Children With Wheezing Montelukast - Wheezing | Phase 4 | Unknown | Universita di Verona | 40 | 2009-09-01 | 2013-06-19 |
| Beneficial Effects of Lactobacillus Reuteri DSM 17938 Supplementation on Asthmatic Children Antileukotrienes + Lactobacillus reuteri, Antileukotrienes + Placebo - Airways Allergic Inflammation of Asthmatic Children | Not applicable | Completed | Federico II University | 50 | 2009-06-01 | 2011-10-03 |
| The Effects of Montelukast on Smokers With Asthma Fluticasone Propionate, Montelukast, Salmeterol - Asthmatic Smokers, Non-asthmatic Smokers | Phase 4 | Completed | Inje University | 105 | 2007-02-01 | 2012-05-16 |
| Childhood Asthma Research and Education (CARE) Network Trial - Acute Intervention Management Strategies (AIMS) Inhaled Corticosteroid (Budesonide), Leukotriene Receptor Antagonist (Montelukast Sodium), Inhaled Albuterol - Asthma, Lung Diseases | Not applicable | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 238 | 2004-02-01 | 2016-07-29 |
Asthma (3) · Chronic Urticaria (2) · Respiratory Sounds (2) · Chronic Periodontitis (1) · Lung Diseases (1) · Rhinitis, Allergic (1) · Urticaria (1)
Bharat Serums and Vaccines Limited (1) · Children's Hospital of Fudan University (1) · Chongqing Medical University (1) · Federico II University (1) · Genentech, Inc. (1) · Guangzhou Institute of Respiratory Disease (1) · Inje University (1) · King Abdullah International Medical Research Center (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Tatyasaheb Kore Dental College (1) · Universita di Verona (1)
China (3) · India (2) · Italy (2) · United States (2) · Australia (1) · Germany (1) · New Zealand (1) · Poland (1) · Saudi Arabia (1) · Singapore (1) · South Korea (1) · Switzerland (1) · United Kingdom (1)
Attilio L Boner, MD (1) · Chang-Keun Kim, MD, PhD (1) · Dr Saswata Banerjee (1) · Edward R. Conner, M.D. (1) · Michele Miraglia del Giudice, MD (1) · Saurabh P Inamdar, BDS (1) · Shen Yang, Doctoral (1) · Vernon M. Chinchilli, PhD (1)
PMID 18973936, PMID 24506412, PMID 26054553, PMID 27424128, PMID 27540466, PMID 27939380, PMID 28390587, PMID 29655772, PMID 36738927
U10HL064287 (1), U10HL064288 (1), U10HL064295 (1), U10HL064305 (1), U10HL064307 (1), U10HL064313 (1)