12 completed, 12 unknown, 10 recruiting, 5 active not recruiting. 23 Phase 2, 13 Phase 3, 6 Not applicable, 5 Phase 4, 4 Phase 1.
Follow Letrozole 2.5mg: new trials by email Literature Review of Letrozole 2.5mg trials Research Report on Letrozole 2.5mg
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Kumorixilib Plus Capecitabine and Letrozole for Neoadjuvant Treatment of HR-Positive HER2-Negative Breast Cancer Kumorixilib 180mg, Capecitabine 500mg, Letrozole 2.5mg - HR+/HER2- Breast Cancer, Breast Neoplasms | Phase 2 | Not yet recruiting | Fujian Cancer Hospital | 35 | 2026-06-30 | 2026-07-08 |
| Use of Aromatase Inhibitor Before Misoprostol in Medical Termination of Miscarriage Letrozole 2.5mg - Miscarriage | Not applicable | Recruiting | Aswan University | 70 | 2025-07-10 | 2025-08-07 |
| Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy Ribociclib 400mg, Letrozole 2.5mg, Anastrazole 1mg - HER2 Negative Breast Cancer | Phase 2 | Recruiting | Yale University | 140 | 2025-07-09 | 2026-05-26 |
| Different Doses of Dalpicicl Combined With Letrozole in the First-line Treatment of HR-positive, HER2-negative Advanced Breast Cancer Dalpiciclib 125mg, Dalpiciclib 150mg, Letrozole 2.5mg - HR Positive HER2 Negative Advanced Breast Cancer | Phase 2 | Recruiting | wanghaibo | 120 | 2025-06-25 | 2025-12-16 |
| Magnesium Oxide and Letrozole Versus Letrozole Alone on Ovarian Response in Insulin Resistant PCOS Experimental drug: Magnesium oxide (365 mg), Letrozole 2.5mg - Insulin Resistant PCOS | Not applicable | Completed | Bangladesh Medical University | 60 | 2025-06-01 | 2026-08-14 |
| Cabergoline & Letrozole Versus Letrozole in Ovulation Induction in PCOS Letrozole 0.5mg, Cabergoline 0.5 mg - PCOS | Not applicable | Recruiting | Mst.Sumyara Khatun | 72 | 2025-02-07 | 2025-12-16 |
| Prescription of Letrozole for Uterine Myoma Letrozole 2.5mg, Placebo - Leiomyoma, Uterine, Leiomyoma | Phase 4 | Recruiting | University of California, San Francisco | 140 | 2024-07-24 | 2026-10-06 |
| Myoinositol, L-arginine and Chromium With Letrozole for Ovulation Induction in Polycystic Ovarian Syndrome Patients Myoinositol, Chromium, l-arginine - Polycystic Ovary Syndrome | Phase 3 | Unknown | Beni-Suef University | 100 | 2024-06-30 | 2024-05-08 |
| Combination Letrozole and Clomiphene Citrate Versus Letrozole Alone Letrozole 2.5mg - Polycystic Ovary Syndrome | Not applicable | Unknown | Egymedicalpedia | 64 | 2024-03-01 | 2024-07-18 |
| Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA) Elacestrant, Tamoxifen, Letrozole 2.5mg - ER-positive Breast Cancer, HER2-negative Breast Cancer | Phase 3 | Recruiting | European Organisation for Research and Treatment of Cancer - EORTC | 220 | 2023-12-15 | 2026-10-07 |
| Comparative Evaluation of the Efficacy of Letrozole, L-Carnitine, and Their Combination on Sperm Quality, Oxidative Stress, and ART Outcomes in Men With Idiopathic Oligoasthenoteratozoospermia. Letrozole 2.5mg, L-carnitine - Idiopathic Oligoasthenoteratozoospermia, Male Infertility | Phase 2 / Phase 3 | Completed | Tehran University of Medical Sciences | 90 | 2023-12-01 | 2026-06-30 |
| Letrozole Dose Increments in PCOS Patients Resistant to Letrozole Letrozole 2.5mg - Polycystic Ovary Syndrome | Phase 3 | Completed | Beni-Suef University | 102 | 2023-10-01 | 2024-05-08 |
| Letrozole Versus Hormonal Preparation in Frozen Cycles of PCOS Patients. Letrozole 2.5mg - Frozen Embryo Transfer, Polycystic Ovarian Disease | Phase 4 | Withdrawn | Dubai Fertility Center | 2023-08-01 | 2024-02-20 | |
| Comparison of Letrozole With Lerociclib Versus Letrozole With Placebo Control in Patients With Advanced/Metastatic or Recurrent, Grade 1 or Grade 2 Endometrial Cancer Lerociclib, Letrozole 2.5mg, Placebo - Endometrial Carcinoma | Phase 3 | Withdrawn | EQRx International, Inc. | 2023-04-18 | 2023-11-03 | |
| Study of Narazaciclib (ON 123300) Plus Letrozole in Endometrial Cancer and Other Gynecologic Malignancies Narazaciclib, Letrozole 2.5mg - Endometrioid Endometrial Cancer | Phase 1 / Phase 2 | Unknown | Traws Pharma, Inc. | 60 | 2023-03-29 | 2023-12-12 |
| Only Gonadotropin Vs. Letrozole Combined Gonadotropin Stimulation in IUI Cycles Letrozole 2.5mg, Gonadotropin - Infertility Unexplained | Not applicable | Completed | Uludag University | 131 | 2023-01-01 | 2024-05-14 |
| Vitamin D and Calcium Supplementation in Breast Cancer Letrozole 2.5mg, Letrozole + vitamin D3 and calcium - Breast Cancer | Phase 2 / Phase 3 | Unknown | Tanta University | 40 | 2022-11-01 | 2023-12-01 |
| Letrozole as Maintenance Therapy for Post-surgical Endometrial Cancer Patients With NSMP Letrozole 2.5mg - Endometrial Cancer | Phase 2 / Phase 3 | Terminated | Fudan University | 12 | 2022-08-02 | 2025-12-15 |
| Study to Evaluate the Extended Overall Survival (OS) Data From PARSIFAL Study (The PARSIFAL-LONG Study) Fulvestrant Injectable Product, Letrozole 2.5mg, Palbociclib 125mg - Metastatic Breast Cancer, Advanced Breast Cancer | Completed | MedSIR | 419 | 2022-07-18 | 2024-12-13 | |
| GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients GnRH antagonist, Letrozole 2.5mg - Endometrial Neoplasms, Atypical Endometrial Hyperplasia | Phase 2 / Phase 3 | Recruiting | Xiaojun Chen | 29 | 2022-07-13 | 2026-09-10 |
Showing 20 of 46. Sign in to see all of them.
Breast Neoplasms (16) · Endometrial Neoplasms (5) · Polycystic Ovary Syndrome (5) · Abortion, Spontaneous (3) · Endometrial Hyperplasia (3) · Progesterone Resistance (3) · Obesity (2) · Abortion, Missed (1) · Carcinoma, Ovarian Epithelial (1) · Fallopian Tube Neoplasms (1) · Helping Behavior (1) · Infertility (1) · Infertility, Female (1) · Infertility, Male (1) · Leiomyoma (1)
Cairo University (3) · Xiaojun Chen (3) · Beni-Suef University (2) · Fudan University (2) · Tanta University (2) · Ahmed Elsayed Aref (1) · Ahon Pharmaceutical Co., Ltd. (1) · Ain Shams Maternity Hospital (1) · Aswan University (1) · Bangladesh Medical University (1) · Blokhin's Russian Cancer Research Center (1) · Dartmouth-Hitchcock Medical Center (1) · Dubai Fertility Center (1) · EQRx International, Inc. (1) · Egymedicalpedia (1)
Egypt (10) · United States (10) · China (8) · Italy (5) · France (4) · Germany (4) · Spain (4) · Austria (2) · Bangladesh (2) · Belgium (2) · Russia (2) · Switzerland (2) · United Kingdom (2) · Brazil (1) · Canada (1)
Al Hassan Mohammad Khedr, Lecturer (1) · Aleix Prat, PhD (1) · Alison Huang, MD, MAS (1) · Antonio Llombart (1) · Ayman Dawood, MD (1) · Azim Hedayatpour, Professor, PhD (1) · Chuangui Song, doctor (1) · Claudia Marchetti (1) · Dina Yahia, Professor (1) · Emmanouil Saloustros (1) · Fernanda Bronzon Damian (1) · Gurkan Uncu, Prof. (1) · Hani Ahmed Farouk, Assist.Prof. (1)
PMID 19380449, PMID 19671625, PMID 21296991, PMID 21737072, PMID 24552218, PMID 31523136, PMID 31838010, PMID 34109484, PMID 35524184, PMID 36067616, PMID 36410913, PMID 38764430, PMID 41697438
2019 (2), R01HD112465 (1)