2 active not recruiting, 2 completed, 1 recruiting, 1 suspended. 4 Phase 3, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 2, Active not recruiting 1, Suspended 1 |
| Phase 2 | 2 | Recruiting 1, Terminated 1 |
| Phase 1 | 1 | Active not recruiting 1 |
Follow Isovorin: new trials by email Literature Review of Isovorin trials Research Report on Isovorin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Blinatumomab - Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia | Phase 2 | Recruiting | National Cancer Institute (NCI) | 153 | 2025-06-05 | 2026-10-27 |
| Study of ONO-4578 and XELOX/FOLFOX Plus Bevacizumab in Colorectal Cancer ONO-4578, ONO-4538, Capecitabine - Colorectal Cancer | Phase 1 | Active not recruiting | Ono Pharmaceutical Co., Ltd. | 40 | 2021-01-13 | 2026-10-22 |
| Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Calaspargase Pegol, Cyclophosphamide - Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia | Phase 3 | Active not recruiting | Children's Oncology Group | 352 | 2017-08-08 | 2026-10-05 |
| Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Treatment Combining Cetuximab With FOLFOX or FOLFIRI in RAS and B-RAF WT Tumors Metastases Resection ( multiple steep surgery possible), 5-Fluorouracile, leucovorin L - Metastatic Colorectal Cancer | Phase 2 | Terminated | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 4 | 2014-01-01 | 2016-04-15 |
| IRIS Followed by mFOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer Campto, Topotesin, TS-1, L-Plat - Metastatic Colorectal Cancer | Phase 3 | Suspended | Hokkaido Gastrointestinal Cancer Study Group | 200 | 2006-04-01 | 2007-11-01 |
| Study Evaluating Isovorin in Colon Cancer Isovorin, UFT - Colon Cancer | Phase 3 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 650 | 2002-10-01 | 2009-08-13 |
| Study Evaluating Isovorin in Advanced/Recurrent Gastric Cancer Isovorin, TS-1 - Gastric Cancer | Phase 3 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 200 | 2002-05-01 | 2009-08-13 |
Colorectal Neoplasms (3) · Burkitt Lymphoma (2) · Leukemia, Biphenotypic, Acute (2) · Colonic Neoplasms (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1) · Stomach Neoplasms (1)
Wyeth is now a wholly owned subsidiary of Pfizer (2) · Children's Oncology Group (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Hokkaido Gastrointestinal Cancer Study Group (1) · National Cancer Institute (NCI) (1) · Ono Pharmaceutical Co., Ltd. (1)
Japan (4) · Belgium (2) · Puerto Rico (2) · United States (2) · Australia (1) · Austria (1) · Canada (1) · Chile (1) · Czechia (1) · Finland (1) · France (1) · Germany (1) · Hong Kong (1) · Israel (1) · Italy (1)
Andrea Biondi (1) · Erin H Breese (1) · Javier Carrasco, MD PhD (1) · Lewis B Silverman (1) · Marc Van den Eynde, MD (1) · Project Leader (1) · Yoshito Komatsu, MD, PhD (1)
U10CA180886 (2), 2017 (1)