15 completed. 15 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Completed 15 |
| Phase 2 | 2 | Completed 2 |
Follow immunologic technique: new trials by email Literature Review of immunologic technique trials Research Report on immunologic technique
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vaccine Therapy Following Therapeutic Autologous Lymphocytes and Cyclophosphamide in Treating Patients With Metastatic Melanoma cyclophosphamide, aldesleukin, autologous tumor cell vaccine - Recurrent Melanoma, Stage IV Melanoma | Phase 1 | Completed | Fred Hutchinson Cancer Center | 12 | 2012-03-01 | 2014-04-21 |
| Panobinostat and Epirubicin in Treating Patients With Metastatic Malignant Solid Tumors epirubicin hydrochloride, panobinostat, gene expression analysis - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | University of California, San Francisco | 40 | 2009-09-13 | 2017-03-24 |
| White Button Mushroom Extract in Treating Patients With Recurrent Prostate Cancer After Local Therapy white button mushroom extract, flow cytometry, immunologic technique - Prostate Cancer | Phase 1 | Completed | City of Hope Medical Center | 36 | 2009-01-29 | 2022-03-31 |
| Hydroxychloroquine and Temsirolimus in Treating Patients With Metastatic Solid Tumors That Have Not Responded to Treatment hydroxychloroquine, temsirolimus, electron microscopy - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | Abramson Cancer Center at Penn Medicine | 40 | 2008-10-01 | 2019-04-16 |
| Monoclonal Antibody Therapy in Treating Patients With Stage IV Melanoma B7-DC cross-linking antibody rHIgM12B7, flow cytometry, immunologic technique - Melanoma (Skin) | Phase 1 | Completed | Mayo Clinic | 7 | 2008-04-08 | 2017-05-25 |
| SB939 in Treating Patients With Locally Advanced or Metastatic Solid Tumors HDAC inhibitor SB939, immunoenzyme technique, immunohistochemistry staining method - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | NCIC Clinical Trials Group | 39 | 2007-09-14 | 2023-08-04 |
| Vaccine Therapy in Treating Patients Who Have Undergone a Donor Stem Cell Transplant and Have Cytomegalovirus Infection That Has Not Responded to Therapy cytomegalovirus pp65-specific cytotoxic T lymphocytes, polymerase chain reaction, diagnostic laboratory biomarker analysis - Cancer | Phase 1 | Completed | University of Louisville | 20 | 2007-06-01 | 2017-05-09 |
| Therapeutic Autologous Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Stage IV Melanoma cyclophosphamide, therapeutic autologous lymphocytes, aldesleukin - Recurrent Melanoma, Stage IV Melanoma | Phase 1 | Completed | Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium | 11 | 2006-12-01 | 2012-03-16 |
| A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies cyclophosphamide, fludarabine phosphate, cyclosporine - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Phase 1 | Completed | Fred Hutchinson Cancer Center | 23 | 2006-04-01 | 2015-02-11 |
| Imiquimod and Laser Therapy With or Without a Green Dye in Treating Patients With Stage III or Stage IV Melanoma That Has Spread to Other Parts of the Skin imiquimod, indocyanine green solution, flow cytometry - Melanoma (Skin), Metastatic Cancer | Phase 1 | Completed | University of Oklahoma | 11 | 2006-03-01 | 2015-05-06 |
| Radiofrequency Therapy-Induced Endogenous Heat-Shock Proteins With or Without Radiofrequency Ablation or Cryotherapy in Treating Patients With Stage IV Melanoma sargramostim, immunoenzyme technique, immunohistochemistry staining method - Melanoma (Skin) | Phase 1 | Completed | Mayo Clinic | 11 | 2005-11-25 | 2018-10-31 |
| Samarium Sm 153 Lexidronam Pentasodium and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma bortezomib, immunologic technique, samarium Sm 153 lexidronam pentasodium - Multiple Myeloma and Plasma Cell Neoplasm | Phase 1 / Phase 2 | Completed | Mayo Clinic | 50 | 2005-09-01 | 2011-05-11 |
| Cetuximab in Treating Patients With Advanced Solid Tumors cetuximab, molecular diagnostic method, immunologic technique - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | University of California, Davis | 27 | 2004-12-01 | 2010-03-29 |
| Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation therapeutic allogeneic lymphocytes, aldesleukin, peripheral blood stem cell transplantation - Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Phase 1 / Phase 2 | Completed | Fred Hutchinson Cancer Center | 37 | 2002-09-01 | 2017-03-29 |
| Vaccine Therapy With Sargramostim (GM-CSF) in Treating Patients With Her-2 Positive Stage III-IV Breast Cancer or Ovarian Cancer pNGVL3-hICD vaccine, sargramostim, flow cytometry - HER2-positive Breast Cancer, Stage III Ovarian Epithelial Cancer | Phase 1 | Completed | University of Washington | 66 | 2001-10-01 | 2025-04-06 |
Melanoma (5) · Congenital Abnormalities (3) · Multiple Myeloma (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Anemia, Refractory, with Excess of Blasts (2) · Breast Neoplasms (2) · Burkitt Lymphoma (2) · Carcinoma, Ovarian Epithelial (2) · Dendritic Cell Sarcoma, Interdigitating (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Leukemia, Myeloid, Accelerated Phase (2) · Leukemia, Myeloid, Acute (2) · Leukemia, Myeloid, Chronic-Phase (2) · Leukemia, Myelomonocytic, Chronic (2) · Lymphoma, B-Cell, Marginal Zone (2)
Fred Hutchinson Cancer Center (3) · Mayo Clinic (3) · Abramson Cancer Center at Penn Medicine (1) · City of Hope Medical Center (1) · Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium (1) · NCIC Clinical Trials Group (1) · University of California, Davis (1) · University of California, San Francisco (1) · University of Louisville (1) · University of Oklahoma (1) · University of Washington (1)
United States (14) · Canada (1)
Angela Davies, MD (1) · Angela Dispenzieri, MD (1) · Cassian Yee (1) · Colleen Delaney (1) · Cy Stein, MD, PhD (1) · Kenneth G. Lucas, MD (1) · Lillian L. Siu, MD, FRCPC (1) · Mark Naylor, MD (1) · Mary L. Disis (1) · Merav Bar (1) · Pamela N. Munster, MD (1) · Ravi Amaravadi, MD (1) · Svetomir Markovic, M.D., Ph.D. (1) · Svetomir N Markovic, MD, PhD (1) · Sylvia Lee (1)
PMID 21285985, PMID 25989179, PMID 26903311, PMID 28679643, PMID 36326756
P30CA015083 (3), K12CA076930 (1), P01CA018029 (1), P30CA033572 (1), P30CA093373 (1), R21CA128283 (1), R24HL074445 (1), R43HL106868 (1), RC2HL101844 (1)