5 completed, 3 recruiting, 2 unknown, 1 active not recruiting. 7 Phase 3, 4 Phase 2, 3 Phase 4, 1 Phase 1.
Follow Immunoglobulin: new trials by email Literature Review of Immunoglobulin trials Research Report on Immunoglobulin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Immunoglobulin Replacement Therapy (IgRT) Versus Antibiotic Prophylaxis (PA) in Patients Treated by CD19-targeted Chimeric Antigen Receptor (CAR)T Cells for a B Cell Acute Lymphoblastic Leukemia or a B Cell Lymphoma Immunoglobulin, antibiotic prophylaxis - Chimeric Antigen Receptor T-cell Therapy, B Cell Acute Lymphoblastic Leukemia (B-ALL) | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 228 | 2026-09-01 | 2026-08-10 |
| Tafasitamab, Retifanlimab, and Rituximab in Combination With Standard Therapy for the Treatment of Diffuse Large B-cell Lymphoma Bone Marrow Biopsy, Cyclophosphamide, Doxorubicin - Diffuse Large B-Cell Lymphoma, Grade 3b Follicular Lymphoma | Phase 1 / Phase 2 | Active not recruiting | University of Washington | 33 | 2023-01-26 | 2026-06-22 |
| China National Registry of Neuro-Inflammatory Diseases Intravenous steroid - Multiple Sclerosis, NMO Spectrum Disorder | Recruiting | Beijing Tiantan Hospital | 10000 | 2021-12-15 | 2023-07-21 | |
| Subcutaneous Immunoglobulin in De-novo CIDP (SIDEC) Immunoglobulin - CIDP - Chronic Inflammatory Demyelinating Polyneuropathy | Phase 4 | Recruiting | University of Aarhus | 60 | 2020-06-04 | 2024-05-17 |
| Randomised Evaluation of COVID-19 Therapy Lopinavir-Ritonavir, Corticosteroid, Hydroxychloroquine - Pneumonia | Phase 3 | Recruiting | University of Oxford | 70000 | 2020-03-19 | 2026-04-21 |
| Study of Immune Globulin Intravenous (Human) GC5101F in Subjects With Primary Humoral Immunodeficiency Immunoglobulin - Primary Immune Deficiency Disorder | Phase 3 | Withdrawn | Green Cross Corporation | 2019-04-30 | 2020-07-07 | |
| The Novel Immunomodulatory and Anticoagulant Therapies for Recurrent Pregnancy Loss Aspirin, Heparin, Prednisone - Recurrent Pregnancy Loss | Phase 4 | Unknown | Shanghai First Maternity and Infant Hospital | 500 | 2014-10-01 | 2017-03-08 |
| Efficacy and Safety of Eculizumab for Treatment of Antibody-mediated Rejection Following Renal Transplantation Eculizumab, Immunoglobulin, Plasmapheresis - Antibody-mediated Rejection, Humoral Rejection | Phase 2 | Terminated | Brigham and Women's Hospital | 11 | 2013-11-01 | 2017-09-21 |
| Immunotherapy and Paraneoplastic Neurological Syndromes Immunoglobulin - Paraneoplastic Neurological Syndromes | Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 17 | 2013-11-01 | 2017-11-06 |
| A Trial to Evaluate the Efficacy of Immunoglobulin Plus Steroid for Prevention of Coronary Artery Abnormalities in Taiwanese Refractory Kawasaki Disease (RAST Study) Prednisolone, immunoglobulin - Kawasaki Disease, Steroid | Phase 3 | Unknown | National Taiwan University Hospital | 100 | 2013-10-17 | 2017-06-27 |
| Phase III Clinical Trial of NPB-01maintenance Therapy in Patients With Multifocal Motor Neuropathy. NPB-01 - Multifocal Motor Neuropathy | Phase 3 | Completed | Nihon Pharmaceutical Co., Ltd | 13 | 2013-04-01 | 2016-01-20 |
| A Study to Evaluate Albumin and Immunoglobulin in Alzheimer's Disease Albumin 5%, Albumin 20%, Immunoglobulin - Alzheimer's Disease | Phase 2 / Phase 3 | Completed | Instituto Grifols, S.A. | 347 | 2012-04-19 | 2019-07-31 |
| Efficacy of High-dose Intravenous Immunoglobulin Therapy for Hyperbilirubinemia Due Rh Hemolytic Disease Intravenous Immunoglobulin, Normal saline solution - Hyperbilirubinemia, Erythroblastosis, Fetal | Phase 4 | Completed | Oswaldo Cruz Foundation | 92 | 2006-10-01 | 2016-01-08 |
| Intravenous Immunoglobulin Therapy in Optic Neuritis Immunoglobulin - Optic Neuritis | Phase 3 | Completed | National Eye Institute (NEI) | 1995-08-01 | 2009-09-17 |
Alzheimer Disease (1) · Burkitt Lymphoma (1) · COVID-19 (1) · Community-Acquired Pneumonia (1) · Demyelinating Autoimmune Diseases, CNS (1) · Encephalomyelitis, Acute Disseminated (1) · Erythroblastosis, Fetal (1) · Hyperbilirubinemia (1) · Lymphoma, B-Cell (1) · Lymphoma, Large B-Cell, Diffuse (1) · Mucocutaneous Lymph Node Syndrome (1) · Multiple Sclerosis (1) · Neoplasms (1) · Neuromyelitis Optica (1) · Optic Neuritis (1)
Assistance Publique - Hôpitaux de Paris (2) · Beijing Tiantan Hospital (1) · Brigham and Women's Hospital (1) · Green Cross Corporation (1) · Instituto Grifols, S.A. (1) · National Eye Institute (NEI) (1) · National Taiwan University Hospital (1) · Nihon Pharmaceutical Co., Ltd (1) · Oswaldo Cruz Foundation (1) · Shanghai First Maternity and Infant Hospital (1) · University of Aarhus (1) · University of Oxford (1) · University of Washington (1)
United States (4) · China (2) · France (2) · Spain (2) · Belgium (1) · Brazil (1) · Denmark (1) · Estonia (1) · Ghana (1) · India (1) · Indonesia (1) · Italy (1) · Japan (1) · Nepal (1) · Netherlands (1)
Anil K Chandraker, MD (1) · Chaim Roifman (1) · Dimitri Psimaras, MD (1) · Henning Andersen, MD,DMSc,PhD (1) · Maria EL Moreira, MD (1) · Mei-Hwan Wu, MD, PhD (1) · Merce Boada Rovira, MD, PhD (1) · Ming-Tai Lin, MD, PhD (1) · Peter W Horby (1) · Stephen D. Smith (1)
PMID 22882285, PMID 29084869, PMID 29635876, PMID 32678530, PMID 33031652, PMID 33031764, PMID 33394942, PMID 33545096, PMID 33933206, PMID 34000257, PMID 34013969, PMID 34473343, PMID 34658014, PMID 34672950, PMID 34800427, PMID 35151397, PMID 35695334, PMID 35713300, PMID 35867135, PMID 35908569, PMID 36522698, PMID 36734509, PMID 37060915, PMID 37162745, PMID 37489818, PMID 37865101, PMID 38272046, PMID 38296965, PMID 38453475, PMID 38489186, PMID 38951929, PMID 39250723, PMID 40036152, PMID 40383127, PMID 40886716, PMID 42578463
2018 (1)