6 completed. 6 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 6 |
| Phase 2 | 3 | Completed 3 |
Follow idebenone: new trials by email Literature Review of idebenone trials Research Report on idebenone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Oral Idebenone to Treat Non-Alcoholic Steatohepatitis Idebenone, Placebo - Non Alcoholic Steatohepatitis, Fibrosis | Phase 1 / Phase 2 | Completed | Stanford University | 53 | 2021-07-30 | 2026-04-24 |
| A Study to Assess the Potential for Pre-systemic Inhibition of CYP3A by Idebenone Using Midazolam as a Substrate Raxone (idebenone 150 mg), Midazolam 2,5 mg - Drug-Drug Interaction | Phase 1 | Completed | Santhera Pharmaceuticals | 32 | 2016-09-01 | 2017-10-05 |
| Idebenone for Primary Progressive Multiple Sclerosis Idebenone - Multiple Sclerosis, Primary Progressive Multiple Sclerosis | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 61 | 2013-03-12 | 2021-05-19 |
| Clinical Trial of Idebenone in Primary Progressive Multiple Sclerosis (IPPoMS) Idebenone, placebo - Primary Progressive Multiple Sclerosis | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 85 | 2009-11-01 | 2019-03-19 |
| Phase 1 Trial of Idebenone to Treat Patients With Friedreich's Ataxia Idebenone - Friedreich Ataxia | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 16 | 2004-02-01 | 2008-03-04 |
| Safety Study of Idebenone to Treat Friedreich's Ataxia Idebenone - Friedreich Ataxia | Phase 1 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 100 | 2001-05-01 | 2006-07-12 |
Friedreich Ataxia (2) · Multiple Sclerosis (2) · Multiple Sclerosis, Chronic Progressive (2) · Nerve Degeneration (2) · Fibrosis (1) · Non-alcoholic Fatty Liver Disease (1)
National Institute of Allergy and Infectious Diseases (NIAID) (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · Santhera Pharmaceuticals (1) · Stanford University (1)
United States (5) · France (1)
Bibiana Bielekova, M.D. (2) · Natalie Torok, MD (1)
PMID 17562928, PMID 19847907, PMID 27574516
R21DK111217 (1)