9 completed, 5 unknown, 4 recruiting, 3 not yet recruiting. 17 Not applicable, 3 Phase 2, 3 Phase 3, 2 Phase 1, 1 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| High Intensity Focused Ultrasound (HIFU) Ablation for Treatment of Prostate Tissue in Bladder Outlet Obstruction High Intensity Focused Ultrasound - Bladder Outlet Obstruction, BPH | Not applicable | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 17 | 2026-11-01 | 2026-10-09 |
| The Efficacy of High-Intensity Focused Ultrasound Therapy on Adenomyosis High Intensity Focused Ultrasound - Adenomyosis of Uterus | Not yet recruiting | Far Eastern Memorial Hospital | 20 | 2026-09-16 | 2026-09-08 | |
| Clinical Evaluation of Linear Z for Body Contouring High Intensity Focused Ultrasound - Non Invasive Body Contouring | Not applicable | Recruiting | Jeisys Medical Inc | 30 | 2026-09-01 | 2026-09-03 |
| High Intensity Focused Ultrasound vs. Cryotherapy in the Treatment of Basal Cell Carcinomas and Bowen's Disease in Adults High Intensity Focused Ultrasound, Cryotherapy - Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma | Not applicable | Not yet recruiting | Jussi Salonen | 294 | 2026-04-01 | 2026-02-03 |
| CUIMC Focal Therapy Registry Focal therapy - Prostate Cancer | Recruiting | Columbia University | 1000 | 2026-01-01 | 2026-06-03 | |
| Safety of the Sonablate HIFU System for the Ablation of Incompetent Veins of the Periphery High Intensity focused ultrasound - Chronic Venous Insufficiency, CVI, Venous Malformations | Not applicable | Active not recruiting | Sonablate | 30 | 2024-09-11 | 2026-02-19 |
| Effect of HIFU on Sleep Quality Measures in Obese Doubled Chin Women high intensity focused ultrasound, Doubled chin exercises - OBESITY | Not applicable | Unknown | Cairo University | 60 | 2024-01-06 | 2024-01-22 |
| Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer Cryosurgery, High-Intensity Focused Ultrasound Ablation, Survey Administration - Localized Prostate Carcinoma, Stage I Prostate Cancer AJCC v8 | Not applicable | Recruiting | University of California, Davis | 100 | 2023-11-09 | 2026-06-30 |
| Effect Of High-Intensity Focused Ultrasound On Abdominal Skin Laxity Post Sleeve Gastrectomy High intensity focused ultrasound, topical firming creams - Skin Laxity, Gastrostomy | Not applicable | Completed | Cairo University | 86 | 2022-06-20 | 2023-08-16 |
| Feasibility of HIFU for Management of Placenta Accreta (HIFU-ACCRETA) High Intensity Focused Ultrasound - Placenta Accreta | Not applicable | Withdrawn | Hospices Civils de Lyon | 2021-11-01 | 2023-11-18 | |
| Comparative Health Research Outcomes of NOvel Surgery in Prostate Cancer Radical therapy (radiotherapy or prostatectomy [radiotherapy can be external beam or brachytherapy], Focal therapy, Focal therapy after Finasteride 5Mg tablets for 12 weeks - Prostate Cancer, Non-metastatic Prostate Cancer | Not applicable | Completed | Imperial College London | 100 | 2019-12-11 | 2025-03-24 |
| Exploring HIFU as a Treatment for Rectal and Other Pelvic Cancers High Intensity Focused Ultrasound - Rectal Cancer, Rectal Neoplasms | Not applicable | Unknown | Imperial College London | 60 | 2019-07-11 | 2019-08-15 |
| A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy High Intensity Focused Ultrasound - Partial Seizures With Secondary Generalization, Focal Epilepsy With Secondary Generalization | Not applicable | Active not recruiting | University of North Carolina, Chapel Hill | 10 | 2018-04-24 | 2026-10-07 |
| High Intensity Focused Ultrasound Guided by MRI as Thermic Destruction in Primitive Small Size Breast Cancer HIGH INTENSITY FOCUSED ULTRASOUND - Breast Cancer | Not applicable | Withdrawn | Centre Antoine Lacassagne | 2017-04-25 | 2018-01-29 | |
| Sonablate HIFU International Registry for PC & BPH Patients High Intensity Focused Ultrasound - Localized Prostate Cancer, BPH (Benign Prostatic Hyperplasia) | Recruiting | Sonablate | 10000 | 2015-01-01 | 2026-08-13 | |
| Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound High Intensity Focused Ultrasound - Breast Fibroadenoma | Not applicable | Completed | David R. Brenin, MD | 20 | 2014-04-01 | 2018-05-07 |
| Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound (HIFU) High Intensity Focused Ultrasound - Breast Fibroadenoma | Not applicable | Completed | University Hospital Tuebingen | 27 | 2013-10-01 | 2024-07-22 |
| Focal Therapy Using HIFU for Localised Prostate Cancer High Intensity Focused Ultrasound - Prostate Cancer | Phase 2 / Phase 3 | Unknown | Jewish General Hospital | 25 | 2013-03-17 | 2017-04-19 |
| High Intensity Focused Ultrasound (HIFU) for Parathyroid Adenoma High Intensity Focused Ultrasound - Parathyroid Adenomas | Not applicable | Terminated | Oxford University Hospitals NHS Trust | 1 | 2011-04-01 | 2017-12-18 |
| Magnetic Resonance-Guided High Intensity Focused Ultrasound for Palliation of Painful Skeletal Metastases Philips MR-guided HIFU system - Bone Metastasis | Phase 1 / Phase 2 | Completed | Philips Healthcare | 10 | 2011-01-01 | 2012-08-29 |
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Prostatic Neoplasms (7) · Leiomyoma (3) · Fibroadenoma (2) · Lower Urinary Tract Symptoms (2) · Myofibroma (2) · Adenomyosis (1) · Blindness, Cortical (1) · Blue rubber bleb nevus syndrome (1) · Bowen's Disease (1) · Breast Neoplasms (1) · Carcinoma, Basal Cell (1) · Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi (1) · Connective Tissue Diseases (1) · Cutis Laxa (1) · Endometrial Neoplasms (1)
Philips Healthcare (4) · Cairo University (2) · Imperial College London (2) · Sonablate (2) · Centre Antoine Lacassagne (1) · Chongqing Medical University (1) · Columbia University (1) · David R. Brenin, MD (1) · Far Eastern Memorial Hospital (1) · Hospices Civils de Lyon (1) · Icahn School of Medicine at Mount Sinai (1) · Jeisys Medical Inc (1) · Jewish General Hospital (1) · Jussi Salonen (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1)
United States (8) · Canada (5) · United Kingdom (3) · Egypt (2) · France (2) · China (1) · Finland (1) · Germany (1) · Mexico (1) · Norway (1) · Taiwan (1)
Clint D. Bahler, MD, MS (1) · David Brenin, MD (1) · Dr. Joseph Chin (1) · Elizabeth David, MD (1) · Erik Fosse, Professor (1) · Franck Bladou, MD (1) · Greg Czarnota, M.D. (1) · Hashim Ahmed (1) · Jamie Murphy, PhD (1) · Jin-Yun Chen, PhD (1) · Juan Qin, PhD (1) · LD Tang, PhD (1)
PMID 23564052, PMID 32302790, PMID 36745000
P30CA093373 (1)