5 completed, 1 unknown. 3 Phase 2, 2 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
| Phase 4 | 1 | Completed 1 |
Follow glybenclamide: new trials by email Literature Review of glybenclamide trials Research Report on glybenclamide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Glyburide Advantage in Malignant Edema and Stroke - Remedy Pharmaceuticals Glyburide for Injection, Placebo - Ischemic Stroke, Malignant Edema | Phase 2 | Completed | Remedy Pharmaceuticals, Inc. | 86 | 2013-06-13 | 2024-11-12 |
| A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus metformin, glybenclamide - Gestational Diabetes Mellitus | Phase 4 | Completed | HaEmek Medical Center, Israel | 108 | 2012-01-01 | 2016-11-01 |
| Glyburide (RP-1127) for Traumatic Brain Injury (TBI) Glyburide, Placebo - Traumatic Brain Injury | Phase 2 | Completed | Remedy Pharmaceuticals, Inc. | 29 | 2011-12-17 | 2024-11-12 |
| Glyburide Advantage in Malignant Edema and Stroke Pilot Glyburide for Injection - Ischemic Stroke | Phase 1 / Phase 2 | Completed | Remedy Pharmaceuticals, Inc. | 10 | 2011-05-26 | 2024-11-22 |
| Safety Study of RP-1127 (Glyburide for Injection) in Healthy Volunteers Glyburide for Injection, Placebo - Traumatic Brain Injury, Stroke | Phase 1 | Completed | Biogen | 34 | 2010-01-07 | 2021-06-21 |
| Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy Metformin, Glybenclamide, NPH insulin - Diabetes Mellitus, Arterial Hypertension | Unknown | Hospital de Clinicas de Porto Alegre | 124 | 2006-07-01 | 2011-10-26 |
Brain Injuries, Traumatic (2) · Ischemic Stroke (2) · Anthrax (1) · Diabetes Mellitus (1) · Diabetes, Gestational (1) · Hypertension (1) · Stroke (1)
Remedy Pharmaceuticals, Inc. (3) · Biogen (1) · HaEmek Medical Center, Israel (1) · Hospital de Clinicas de Porto Alegre (1)
United States (4) · Brazil (1) · Israel (1)
Jorge L Gross, MD, PhD (1) · Rogerio Friedman, MD, PhD (1)
PMID 24193798, PMID 27567243, PMID 28077460, PMID 29789393, PMID 30446594, PMID 31537189, PMID 31787498