2 completed, 1 active not recruiting, 1 no longer available, 1 terminated. 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Active not recruiting 1 |
| Phase 2 | 2 | Terminated 1, Withdrawn 1 |
Follow Flotetuzumab: new trials by email Literature Review of Flotetuzumab trials Research Report on Flotetuzumab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post-transplant Flotetuzumab for AML Flotetuzumab - Leukemia, Myeloid, Acute | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 3 | 2022-10-20 | 2025-09-12 |
| Study to Assess an Interphase Cycle With Flotetuzumab. Flotetuzumab - AML | Phase 2 | Withdrawn | Stichting Hemato-Oncologie voor Volwassenen Nederland | 2022-01-01 | 2021-12-22 | |
| Flotetuzumab for Relapsed Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Following Allogeneic Hematopoietic Cell Transplantation (Allo-HCT) Flotetuzumab, Donor lymphocyte infusion - Relapsed Acute Myeloid Leukemia | Phase 2 | Terminated | Washington University School of Medicine | 11 | 2021-05-20 | 2024-12-06 |
| Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies Acetaminophen, Dexamethasone, Diphenhydramine - Recurrent Acute Leukemia, Recurrent B Acute Lymphoblastic Leukemia | Phase 1 | Completed | City of Hope Medical Center | 13 | 2020-11-18 | 2026-01-28 |
| Flotetuzumab for the Treatment of Pediatric Recurrent or Refractory Acute Myeloid Leukemia Cytarabine, Flotetuzumab - Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia | Phase 1 | Active not recruiting | Children's Oncology Group | 16 | 2020-01-22 | 2026-08-24 |
| Flotetuzumab Expanded Access Program flotetuzumab - Acute Myeloid Leukemia, AML | No longer available | MacroGenics | 2022-05-31 |
Leukemia, Myeloid, Acute (4) · Blastic Plasmacytoid Dendritic Cell Neoplasm (1) · Burkitt Lymphoma (1) · Hematologic Neoplasms (1) · Hodgkin Disease (1) · Leukemia, Hairy Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Mastocytosis, Systemic (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1) · Recurrence (1)
Children's Oncology Group (1) · City of Hope Medical Center (1) · MacroGenics (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · Stichting Hemato-Oncologie voor Volwassenen Nederland (1) · Washington University School of Medicine (1)
United States (4) · Netherlands (1)
Adam J Lamble (1) · Ashley Ward, MD (1) · Ibrahim T Aldoss (1) · Jonathan Webster, MD (1) · M. Jongen-Lavrencic, PhD (1) · Matthew Christopher, M.D., Ph.D. (1)
P01CA015396 (1), P30CA033572 (1), P50CA171963 (1), UM1CA228823 (1)