4 completed, 1 not yet recruiting, 1 terminated. 6 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Not yet recruiting 1, Terminated 1 |
| Phase 3 | 2 | Completed 1, Not yet recruiting 1 |
Follow F8 protein, human: new trials by email Literature Review of F8 protein, human trials Research Report on F8 protein, human
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low Dose Emicizumab vs Low Dose Factor VIII in Prophylaxis in Hemophilia A Patients Emicizumab Injection, Factor VIII (FVIII) - Hemophilia A | Phase 2 / Phase 3 | Not yet recruiting | Dhaka Medical College | 20 | 2025-06-01 | 2025-04-22 |
| Weight-based Dosing in Hemophilia A rFVIII - Hemophilia | Phase 2 | Terminated | Craig Seaman | 30 | 2015-09-01 | 2020-09-25 |
| An Open-label Safety, Efficacy and Pharmacokinetic Study of a Recombinant FVIII Compared to Recombinant Human Antihemophilic FVIII in Patients With Severe Hemophilia A rVIII-SingleChain, Octocog alfa - Hemophilia A | Phase 2 / Phase 3 | Completed | CSL Behring | 175 | 2012-02-01 | 2016-08-09 |
| Clinical Study to Investigate the Pharmacokinetics, Efficacy, Safety and Immunogenicity of a Recombinant FVIII in Patients With Severe Hemophilia A Human-cl rhFVIII, Kogenate FS - Hemophilia A | Phase 2 | Completed | Octapharma | 22 | 2010-05-01 | 2019-10-08 |
| Once-A-Day Prophylaxis for Youth and Young Adults With Severe Hemophilia A Kogenate FS, Advate, or Humate-P, Recombinate, Helixate FS - Hemophilia A | Phase 2 | Completed | The Hospital for Sick Children | 14 | 2008-07-01 | 2020-10-08 |
| Study of the Efficacy of Human Recombinant Factor VIII (Kogenate FS) Reconstituted in Pegylated Liposomes. Kogenate FS, reconstituted in a suspension of liposomes - Haemophilia A | Phase 2 | Completed | Recoly N.V. | 16 | 2005-10-01 | 2007-10-16 |
Hemophilia A (6) · Hemostatic Disorders (1)
CSL Behring (1) · Craig Seaman (1) · Dhaka Medical College (1) · Octapharma (1) · Recoly N.V. (1) · The Hospital for Sick Children (1)
United States (3) · Canada (2) · Germany (2) · Russia (2) · Australia (1) · Austria (1) · Bangladesh (1) · Bulgaria (1) · Czechia (1) · Hungary (1) · Italy (1) · Japan (1) · Lebanon (1) · Malaysia (1) · Netherlands (1)
Akhil R. Biswas, MBBS, FCPS (1) · Brian Feldman, MD,MSc,FRCPC (1) · Craig Seaman, MD, MS (1) · Jack Spira, MD. PhD. (1) · Sigurd Knaub, PhD (1)