5 completed, 2 unknown. 7 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 5, Unknown 2 |
Follow F8 protein, human: new trials by email Literature Review of F8 protein, human trials Research Report on F8 protein, human
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacokinetic Assessment of Standard Half-Life (SHL) FVIII, Extended Half-Life (EHL) FVIII, and Efanesoctocog Alfa (BIVV001) in Severe Hemophilia A Efanesoctocog alfa, Octocog alfa, Rurioctocog alfa pegol - Hemophilia A | Phase 1 | Completed | Sanofi | 13 | 2021-08-11 | 2025-09-18 |
| Pharmacokinetics Evaluation of Recombinant Coagulation Factor VIII Injection in Subjects With Hemophilia A. Xyntha, Recombinant Coagulation Factor VIII Injection - Hemophilia A | Phase 1 | Unknown | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 24 | 2019-05-08 | 2019-08-19 |
| Pharmacokinetic Study of SCT800 in Previously Treated Patients With Hemophilia A SCT800, Xyntha - Hemophilia A | Phase 1 | Unknown | Sinocelltech Ltd. | 16 | 2016-09-01 | 2016-09-02 |
| BAX 826 Dose-Escalation Safety Study BAX 826, Octocog alfa - Hemophilia A | Phase 1 | Completed | Baxalta now part of Shire | 40 | 2016-03-03 | 2021-05-25 |
| Comparative Pharmacokinetic Study of Two Different Strengths of BAY14-2222 Recombinant Factor VIII (Kogenate FS, BAY14-2222) - Hemophilia A | Phase 1 | Completed | Bayer | 18 | 2012-07-01 | 2014-01-10 |
| Trial to Evaluate the Pharmacokinetics and Safety Profile of BAY94-9027 Following Single and Multiple Dose Administration BAY94-9027 + Recombinant Factor VIII (Kogenate FS, BAY14-2222), BAY94-9027 + Recombinant Factor VIII (Kogenate FS, BAY14-2222)) - Hemophilia A | Phase 1 | Completed | Bayer | 14 | 2010-10-13 | 2018-09-07 |
| Pharmacokinetics and Safety of a Single Intravenous Infusion of BAY 79-4980 Recomb. Factor VIII (Kogenate FS Liposome, BAY79-4980), Recombinant Factor VIII (Kogenate FS, BAY14-2222) - Hemophilia A | Phase 1 | Completed | Bayer | 27 | 2005-09-01 | 2014-11-18 |
Hemophilia A (7)
Bayer (3) · Baxalta now part of Shire (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · Sanofi (1) · Sinocelltech Ltd. (1)
Bulgaria (3) · China (2) · United States (2) · Germany (1) · Hungary (1) · Italy (1) · Netherlands (1) · Poland (1) · Russia (1) · Spain (1) · United Kingdom (1)
PMID 24843882, PMID 31778283, PMID 37538505
2015 (1)