22 completed, 4 terminated. 20 Phase 1, 4 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 20 | Completed 20 |
| Phase 3 | 4 | Terminated 4 |
| Phase 2 | 2 | Completed 2 |
Follow evacetrapib: new trials by email Literature Review of evacetrapib trials Research Report on evacetrapib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Different Particle Sizes of Evacetrapib in Healthy Participants Evacetrapib - Healthy | Phase 1 | Completed | Eli Lilly and Company | 95 | 2015-07-01 | 2018-12-03 |
| A Study of Evacetrapib (LY2484595) in Combination With Atorvastatin in Japanese Participants With Primary Hypercholesterolemia Evacetrapib, Ezetimibe, Atorvastatin - Hypercholesterolemia | Phase 3 | Terminated | Eli Lilly and Company | 149 | 2015-01-01 | 2018-10-09 |
| A Study to Evaluate the Effect of Increased Stomach pH on Evacetrapib in Healthy Participants Evacetrapib, Omeprazole - Healthy | Phase 1 | Completed | Eli Lilly and Company | 34 | 2015-01-01 | 2018-10-03 |
| A Study of Evacetrapib (LY2484595) in Japanese Participants With Primary Hypercholesterolemia Evacetrapib, Placebo - Hypercholesterolemia | Phase 3 | Terminated | Eli Lilly and Company | 54 | 2014-11-01 | 2018-10-09 |
| A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol Evacetrapib, Atorvastatin, Ezetimibe - Hyperlipidemia | Phase 3 | Terminated | Eli Lilly and Company | 366 | 2014-10-01 | 2019-10-08 |
| A Study to Measure the Amount of Evacetrapib That Enters the Blood Stream in Healthy Participants Evacetrapib Tablet, Evacetrapib Intravenous - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 8 | 2014-10-01 | 2019-03-01 |
| A Study of Evacetrapib in Healthy Japanese Participants Evacetrapib - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 48 | 2014-09-01 | 2018-11-08 |
| Study of Evacetrapib (LY2484595) and Warfarin in Healthy Participants Evacetrapib, Warfarin - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 24 | 2014-06-01 | 2018-10-03 |
| A Study of Evacetrapib With Selected Statins in Healthy Chinese Participants Evacetrapib, Simvastatin, Atorvastatin - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 62 | 2014-06-01 | 2018-10-10 |
| A Study of Evacetrapib in Participants With Abnormal Cholesterol Evacetrapib - Dyslipidemia | Phase 1 | Completed | Eli Lilly and Company | 101 | 2014-05-01 | 2018-10-03 |
| A Study of Evacetrapib in Japanese and Non-Japanese Participants Evacetrapib, Pravastatin - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 24 | 2013-10-01 | 2018-10-09 |
| A Study of Evacetrapib and Rifampin in Healthy Participants Evacetrapib, Rifampin - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 26 | 2013-07-01 | 2018-10-03 |
| A Study of Evacetrapib (LY2484595) in Healthy Participants Evacetrapib - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 60 | 2013-07-01 | 2018-10-09 |
| A Study of Evacetrapib and Digoxin in Healthy Participants Evacetrapib, Digoxin - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 16 | 2013-07-01 | 2018-10-09 |
| A Study of Evacetrapib (LY2484595) in Participants With Severe Renal Impairment and in Healthy Participants Evacetrapib - Cardiovascular Disease | Phase 1 | Completed | Eli Lilly and Company | 20 | 2013-04-01 | 2018-10-09 |
| A Study of Evacetrapib (LY2484595) in Participants With Hepatic (Liver) Impairment Evacetrapib - Hepatic Insufficiency | Phase 1 | Completed | Eli Lilly and Company | 32 | 2013-04-01 | 2018-10-12 |
| A Study of Evacetrapib (LY2484595) and Warfarin in Healthy Participants Evacetrapib, Warfarin - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 17 | 2013-04-01 | 2018-10-09 |
| Study of Food on Evacetrapib (LY2484595) in Healthy Participants Evacetrapib, High-fat Meal - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 40 | 2013-03-01 | 2018-10-12 |
| A Study of Evacetrapib in Healthy Female Participants Ortho-Cyclen, Evacetrapib - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 23 | 2012-12-01 | 2018-10-09 |
| A Study of Evacetrapib in Healthy Participants Evacetrapib, Gemfibrozil - Healthy Volunteers | Phase 1 | Completed | Eli Lilly and Company | 24 | 2012-12-01 | 2018-10-03 |
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Dyslipidemias (3) · Hypercholesterolemia (3) · Cardiovascular Diseases (2) · Atherosclerosis (1) · Hepatic Insufficiency (1) · Hyperlipidemias (1) · Lipid Metabolism Disorders (1) · Metabolic Diseases (1)
United States (18) · Japan (5) · United Kingdom (4) · China (2) · Denmark (2) · Germany (2) · Netherlands (2) · Poland (2) · Puerto Rico (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1) · Brazil (1) · Bulgaria (1)
PMID 22089718, PMID 26564598, PMID 27206939, PMID 28412650, PMID 28514624, PMID 31752637, PMID 31852422, PMID 32639518