15 completed, 3 unknown, 1 terminated, 1 withdrawn. 20 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 20 | Completed 15, Unknown 3, Terminated 1, Withdrawn 1 |
| Phase 1 | 4 | Completed 3, Unknown 1 |
Follow estramustine phosphate sodium: new trials by email Literature Review of estramustine phosphate sodium trials Research Report on estramustine phosphate sodium
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Docetaxel, Estramustine, and Thalidomide in Treating Patients With Androgen-Independent Metastatic Adenocarcinoma of the Prostate docetaxel, estramustine phosphate sodium, thalidomide - Prostate Cancer | Phase 2 | Completed | National Institutes of Health Clinical Center (CC) | 60 | 2004-03-01 | 2012-03-15 |
| Paclitaxel, Topotecan, and Estramustine in Treating Patients With Metastatic Hormone-Refractory Prostate Cancer estramustine phosphate sodium, paclitaxel, topotecan hydrochloride - Prostate Cancer | Phase 2 | Withdrawn | Fox Chase Cancer Center | 2003-11-01 | 2013-07-10 | |
| Isotretinoin, Interferon Alfa-2b, Docetaxel, and Estramustine in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy recombinant interferon alfa-2b, docetaxel, estramustine phosphate sodium - Prostate Cancer | Phase 2 | Terminated | University of Medicine and Dentistry of New Jersey | 40 | 2002-11-01 | 2009-12-11 |
| Docetaxel, Estramustine, and Exisulind in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy docetaxel, estramustine phosphate sodium, exisulind - Prostate Cancer | Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 80 | 2002-11-01 | 2016-07-01 |
| S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer bicalutamide, estramustine, etoposide - Prostate Cancer | Phase 2 | Completed | SWOG Cancer Research Network | 41 | 2001-12-01 | 2013-07-16 |
| Docetaxel, Estramustine, and Thalidomide in Treating Patients With Prostate Cancer Previously Treated With Hormone Therapy docetaxel, estramustine phosphate sodium, thalidomide - Prostate Cancer | Phase 2 | Completed | Nuvance Health | 2001-09-01 | 2013-04-04 | |
| Ixabepilone With or Without Estramustine in Treating Patients With Progressive Prostate Cancer estramustine phosphate sodium, ixabepilone - Prostate Cancer | Phase 1 / Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 2001-07-01 | 2013-06-24 | |
| Combination Chemotherapy Plus Bevacizumab in Treating Patients With Metastatic Prostate Cancer estramustine phosphate sodium, docetaxel, bevacizumab - Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 72 | 2001-06-01 | 2013-06-05 |
| Chemotherapy With or Without Biological Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy recombinant interferon alfa, estramustine phosphate sodium, isotretinoin - Prostate Cancer | Phase 2 | Completed | Eastern Cooperative Oncology Group | 2001-04-05 | 2023-06-22 | |
| Combination Chemotherapy Plus Warfarin in Treating Patients With Prostate Cancer docetaxel, doxorubicin hydrochloride, estramustine phosphate sodium - Prostate Cancer, Thromboembolism | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 2000-09-01 | 2013-01-16 | |
| Combination Chemotherapy Plus Filgrastim in Treating Patients With Stage IV Prostate Cancer That Has Not Responded to Hormone Therapy filgrastim, carboplatin, docetaxel - Prostate Cancer | Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 40 | 2000-03-01 | 2016-07-14 |
| Paclitaxel Plus Estramustine in Treating Patients With Metastatic Prostate Cancer estramustine phosphate sodium, paclitaxel - Prostate Cancer | Phase 2 | Completed | Eastern Cooperative Oncology Group | 1999-02-04 | 2023-06-15 | |
| Paclitaxel Plus Estramustine in Treating Patients With Metastatic Prostate Cancer estramustine phosphate sodium, paclitaxel - Prostate Cancer | Phase 2 | Unknown | St. Barnabas Medical Center | 17 | 1998-10-01 | 2013-12-19 |
| Combination Chemotherapy in Treating Patients With Advanced Cancer estramustine phosphate sodium, paclitaxel, vinorelbine ditartrate - Leukemia, Lymphoma | Phase 1 / Phase 2 | Completed | NYU Langone Health | 1998-09-01 | 2011-03-28 | |
| Combination Chemotherapy With or Without Prednisone in Treating Patients With Recurrent and/or Metastatic Kidney Cancer estramustine phosphate sodium, prednisone, vinorelbine tartrate - Kidney Cancer | Phase 2 | Completed | University of New Mexico | 35 | 1998-07-01 | 2016-05-12 |
| Combination Chemotherapy in Treating Patients With Advanced Prostate Cancer carboplatin, endocrine-modulating drug therapy, estramustine phosphate sodium - Prostate Cancer | Phase 1 / Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 18 | 1998-04-01 | 2013-06-24 |
| Docetaxel Plus Estramustine in Treating Patients With Metastatic Prostate Cancer docetaxel, estramustine phosphate sodium - Prostate Cancer | Phase 1 / Phase 2 | Unknown | Herbert Irving Comprehensive Cancer Center | 37 | 1998-02-01 | 2014-01-06 |
| Combination Chemotherapy With Ketoconazole in Treating Patients With Prostate Cancer Doxorubicin Hydrochloride, Estramustine phosphate sodium, Etoposide - Prostate Cancer | Phase 2 | Completed | M.D. Anderson Cancer Center | 75 | 1997-12-01 | 2012-07-30 |
| Docetaxel Combined With Estramustine in Treating Women With Metastatic Breast Cancer docetaxel, estramustine phosphate sodium - Breast Cancer | Phase 2 | Unknown | Herbert Irving Comprehensive Cancer Center | 40 | 1997-02-01 | 2014-01-06 |
| Paclitaxel and Estramustine in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma estramustine phosphate sodium, paclitaxel - Lymphoma | Phase 2 | Completed | Fox Chase Cancer Center | 25 | 1996-02-01 | 2013-07-10 |
Prostatic Neoplasms (16) · Burkitt Lymphoma (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Lymphoma (2) · Lymphoma, B-Cell, Marginal Zone (2) · Lymphoma, Follicular (2) · Lymphoma, Large B-Cell, Diffuse (2) · Lymphoma, Large-Cell, Immunoblastic (2) · Lymphoma, Mantle-Cell (2) · Lymphoma, Non-Hodgkin (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Breast Neoplasms (1) · Carcinoma, Renal Cell (1) · Fibrosarcoma (1) · Hodgkin Disease (1)
Memorial Sloan Kettering Cancer Center (3) · Alliance for Clinical Trials in Oncology (2) · Eastern Cooperative Oncology Group (2) · Fox Chase Cancer Center (2) · Herbert Irving Comprehensive Cancer Center (2) · M.D. Anderson Cancer Center (1) · NYU Langone Health (1) · National Cancer Institute (NCI) (1) · National Institutes of Health Clinical Center (CC) (1) · Nuvance Health (1) · SWOG Cancer Research Network (1) · St. Barnabas Medical Center (1) · University of Medicine and Dentistry of New Jersey (1) · University of New Mexico (1)
United States (19) · Canada (1) · Puerto Rico (1) · South Africa (1)
Gary R. Hudes, MD (2) · Robert S. DiPaola, MD (2) · William K. Kelly, DO (2) · Amy D. Tiersten, MD (1) · Avi S. Retter, MD (1) · Daniel P. Petrylak, MD (1) · David C. Smith, MD (1) · Franco M. Muggia, MD (1) · Joel Picus (1) · Laurence Elias, MD (1) · Michael Morris, MD (1) · Mitchell R. Smith, MD, PhD (1) · Nancy Dawson, MD (1) · Randall E. Millikan, MD, PhD (1) · Richard C. Frank, MD (1)
PMID 12610188, PMID 14504052, PMID 14669278, PMID 15735119, PMID 18824434
U10CA031946 (3), P30CA006927 (1), P30CA016087 (1), P30CA016672 (1), P30CA072720 (1), U10CA032102 (1)