2 completed, 2 withdrawn, 1 recruiting. 3 Phase 3, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Withdrawn 2, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Denifanstat: new trials by email Literature Review of Denifanstat trials Research Report on Denifanstat
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 3 Study of Denifanstat in Participants With Moderate to Severe Acne (AURORA) Denifanstat, Placebo - Acne Vulgaris | Phase 3 | Recruiting | Sagimet Biosciences Inc. | 800 | 2026-10-01 | 2026-10-23 |
| A Drug-Drug Interaction Study of Denifanstat and Resmetirom in Healthy Adult Participants Denifanstat, Resmetirom - Healthy | Phase 1 | Completed | Sagimet Biosciences Inc. | 40 | 2025-09-30 | 2026-01-23 |
| A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASH and F2/F3 Fibrosis Denifanstat, Placebo - MASH, NASH | Phase 3 | Withdrawn | Sagimet Biosciences Inc. | 2025-03-01 | 2025-05-15 | |
| A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASLD and MASH denifanstat, Placebo - MASLD, MASH | Phase 3 | Withdrawn | Sagimet Biosciences Inc. | 2025-03-01 | 2025-05-15 | |
| TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer Anastrozole, Denifanstat, Exemestane - Advanced Breast Carcinoma, HER2-Positive Breast Carcinoma | Phase 2 | Completed | Mayo Clinic | 17 | 2017-08-03 | 2026-10-09 |
Fatty Liver (2) · Non-alcoholic Fatty Liver Disease (2) · Acne Vulgaris (1) · Fibrosis (1)
Sagimet Biosciences Inc. (4) · Mayo Clinic (1)
United States (3)