darapladib: Clinical Trials

13 completed. 13 Phase 1.

By phase and status

Phase	Trials	Status
Phase 1	13	Completed 13

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Trials (filtered) newest first · largest first

All 13 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Effect of Darapladib on Cantharidin-Induced Inflammatory Blisters in Subjects With Type 2 Diabetes Mellitus (T2DM) Darapladib - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	9	2014-02-26	2017-05-15
Darapladib China PK darapladib 160mg - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	24	2013-10-23	2017-05-15
Pharmacokinetic Interaction of Darapladib and CYP 3A4 in Healthy Subjects Darapladib, Midazolam - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	26	2013-06-19	2017-05-15
Study to Determine the Effect of Repeated Administration of Diltiazem on the Pharmacokinetics of Darapladib (Sb-480848). Darapladib, Diltiazem - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	36	2013-05-14	2017-07-13
To Estimate the Potential Effects of Repeat Doses of Darapladib on the Pharmacokinetics (PK) of Rosuvastatin as Well as Evaluating Safety and Tolerability in Healthy Volunteers Rosuvastatin 10 mg, Darapladib 160 mg - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	18	2012-12-17	2017-07-26
A Study to Assess the Pharmacokinetics, Safety and Tolerability of Repeat Oral Doses of Darapladib (SB-480848) in Subjects With Severe Renal Impairment Darapladib 160 mg - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	16	2012-10-29	2017-07-26
Study to Evaluate Darapladib in Moderately Hepatically Impaired Subjects darapladib - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	24	2010-07-01	2017-07-26
A Healthy Volunteer Pharmacokinetic Study of Single and Repeat Doses of SB-480848 darapladib - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	20	2008-09-01	2016-11-16
A Study With Darapladib to Collect Tolerability Information SB-480848 (darapladib) - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	2	2008-05-01	2016-11-04
Phase I Study of SB-480848(Darapladib) -Repeat Dose Study in Healthy Japanese Male Subjects- SB-480848 (Darapladib) - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	18	2008-01-01	2016-11-03
A Study Investigating the Concentrations of Darapladib in Blood and the Safety of This Compound in Healthy Japanese Men Darapladib (SB480848) - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	18	2007-07-01	2016-12-05
Study Of The Effects Of SB 480848 (Darapladib) On The Electrical Conduction Of The Heart Darapladib - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	72	2006-12-01	2016-10-28
A Study To Determine The Effect Of SB-480848 On Asthma SB 480848, tablets - Atherosclerosis	Phase 1	Completed	GlaxoSmithKline	67	2006-08-01	2016-12-05

Conditions studied

Atherosclerosis (13)  ·  Asthma (1)  ·  Diabetes Mellitus, Type 2 (1)  ·  Renal Insufficiency (1)

Sponsors

GlaxoSmithKline (13)

Countries

United States (10)  ·  China (1)  ·  Germany (1)  ·  Japan (1)  ·  United Kingdom (1)

Results publications

PMID 26465780