75 active not recruiting. 75 Phase 1, 25 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 75 | Active not recruiting 75 |
| Phase 2 | 25 | Active not recruiting 25 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anti-CD19/20/22 Chimeric Antigen Receptor T Cells (TriCAR19.20.22 T Cells) for the Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, and Chronic Lymphocytic Leukemia Autologous Anti-CD19/CD20/CD22 CAR T-cells, Biospecimen Collection, Bone Marrow Aspiration - Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive, Recurrent Acute Lymphoblastic Leukemia | Phase 1 | Active not recruiting | Ohio State University Comprehensive Cancer Center | 24 | 2026-01-14 | 2026-08-26 |
| Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers Computed Tomography, Fludeoxyglucose F-18, Gallium Ga 68 FAPi-46 - Anal Carcinoma, Bladder Carcinoma | Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 30 | 2025-08-01 | 2026-10-20 |
| Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer Biopsy, Biospecimen Collection, Bone Scan - Breast Carcinoma, Colorectal Carcinoma | Phase 1 | Active not recruiting | City of Hope Medical Center | 24 | 2025-05-27 | 2026-10-05 |
| Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer Biopsy, Biospecimen Collection, Computed Tomography - Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Peritoneum | Phase 1 | Active not recruiting | Arjun Mittra | 9 | 2024-12-31 | 2026-10-09 |
| Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer Biopsy, Bone Scan, Computed Tomography - Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 1 | Active not recruiting | Roswell Park Cancer Institute | 3 | 2024-12-19 | 2026-08-07 |
| MC210808 Venetoclax in Combination With Lenalidomide and Dexamethasone (Ven-Rd), Daratumumab and Dexamethasone (Ven-Dd), or Daratumumab-Lenalidomide-Dexamethasone (Ven-DRd) for the Treatment of Multiple Myeloma Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Multiple Myeloma | Phase 1 | Active not recruiting | Mayo Clinic | 16 | 2024-04-11 | 2026-08-17 |
| Elotuzumab, CC-92480, and Dexamethasone for the Treatment of Relapsed or Refractory Myeloma After CD38- and BCMA-Targeted Therapies Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Multiple Myeloma, Refractory Multiple Myeloma | Phase 1 | Active not recruiting | Abdullah Khan | 12 | 2023-12-21 | 2026-05-13 |
| Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis Aldesleukin, Biopsy Procedure, Biospecimen Collection - Clinical Stage IV Gastric Cancer AJCC v8, Gastric Adenocarcinoma | Phase 1 | Active not recruiting | Mayo Clinic | 15 | 2023-11-29 | 2026-07-01 |
| Radioligand Therapy After PSMA PET Guided External Beam Radiotherapy for Treating Post-Prostatectomy Patients With Biochemically Recurrent Prostate Cancer Biospecimen Collection, Computed Tomography, External Beam Radiation Therapy - Biochemically Recurrent Prostate Carcinoma, Prostate Adenocarcinoma | Phase 1 | Active not recruiting | Emory University | 6 | 2023-11-29 | 2025-12-09 |
| Vaccine Therapy Plus Pembrolizumab in Treating Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer Biopsy, Biospecimen Collection, Computed Tomography - Fallopian Tube Carcinosarcoma, Primary Peritoneal Carcinosarcoma | Phase 1 / Phase 2 | Active not recruiting | Mayo Clinic | 38 | 2023-09-28 | 2026-09-21 |
| Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers Biopsy Procedure, Biospecimen Collection, Cobimetinib - Advanced Endometrial Carcinoma, Metastatic Endometrial Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 42 | 2023-09-14 | 2026-10-09 |
| Testing the Safety of the Anti-Cancer Drugs Durvalumab and Olaparib During Radiation Therapy for Locally Advanced Unresectable Pancreatic Cancer Biopsy Procedure, Biospecimen Collection, Computed Tomography - Locally Advanced Pancreatic Carcinoma, Stage II Pancreatic Cancer AJCC v8 | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 18 | 2023-05-22 | 2026-07-10 |
| Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy Balstilimab, Biospecimen Collection, Botensilimab - Advanced Colorectal Adenocarcinoma, Advanced Microsatellite Stable Colorectal Carcinoma | Phase 1 / Phase 2 | Active not recruiting | City of Hope Medical Center | 28 | 2023-05-11 | 2026-09-01 |
| FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer Balstilimab, Bevacizumab, Biospecimen Collection - Metastatic Colon Adenocarcinoma, Metastatic Colorectal Adenocarcinoma | Phase 1 / Phase 2 | Active not recruiting | City of Hope Medical Center | 20 | 2023-05-03 | 2026-09-01 |
| Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers Biospecimen Collection, Computed Tomography, Ipatasertib - FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma | Phase 1 / Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 96 | 2023-03-31 | 2026-10-01 |
| Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment Belinostat, Biopsy Procedure, Biospecimen Collection - Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 48 | 2023-03-01 | 2026-09-18 |
| Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors Atezolizumab, Biospecimen Collection, Computed Tomography - Atypical Teratoid/Rhabdoid Tumor, Epithelioid Sarcoma | Phase 1 / Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 86 | 2022-11-17 | 2026-07-14 |
| Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis Biospecimen Collection, Bone Marrow Aspiration and Biopsy, Computed Tomography - Recurrent AL Amyloidosis, Refractory AL Amyloidosis | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 24 | 2022-08-03 | 2026-07-31 |
| Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer Biopsy Procedure, Biospecimen Collection, Computed Tomography - Extensive Stage Lung Small Cell Carcinoma, Limited Stage Lung Small Cell Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 18 | 2022-07-27 | 2026-05-13 |
| Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy Biospecimen Collection, Bone Scan, Computed Tomography - Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis Urothelial Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 24 | 2022-07-07 | 2026-09-22 |
Showing 20 of 75. Sign in to see all of them.
Neoplasm Metastasis (13) · Colorectal Neoplasms (9) · Lung Neoplasms (9) · Ovarian Neoplasms (6) · Pancreatic Neoplasms (6) · Prostatic Neoplasms (6) · Breast Neoplasms (5) · Carcinoma, Non-Small-Cell Lung (5) · Carcinoma, Transitional Cell (5) · Fallopian Tube Neoplasms (5) · Melanoma (5) · Urinary Bladder Neoplasms (5) · Carcinoma, Hepatocellular (4) · Carcinoma, Renal Cell (4) · Neuroendocrine Tumors (4)
National Cancer Institute (NCI) (49) · Mayo Clinic (8) · M.D. Anderson Cancer Center (4) · City of Hope Medical Center (3) · Jonsson Comprehensive Cancer Center (3) · Abdullah Khan (1) · Arjun Mittra (1) · ECOG-ACRIN Cancer Research Group (1) · Emory University (1) · Flemming Forsberg (1) · Ohio State University Comprehensive Cancer Center (1) · Roswell Park Cancer Institute (1) · SWOG Cancer Research Network (1)
United States (75) · Canada (8) · Australia (1) · Norway (1) · Puerto Rico (1)
Jeremie Calais (3) · Joyce F Liu (2) · Liza C Villaruz (2) · Marwan G Fakih (2) · Timothy A Yap (2) · A P Chen (1) · Abdullah M Khan, MBBS, MSc (1) · Alex F Herrera (1) · Alvaro J Alencar (1) · Andrea B Apolo (1) · Anish Thomas (1) · Anjali S Advani (1) · Arjun Mittra, MD (1) · Armeen Mahvash (1) · Beth A Christian (1)
PMID 23810467, PMID 25218906, PMID 32853585, PMID 32915679, PMID 35031545, PMID 35205614, PMID 35264434, PMID 36997799, PMID 37185961, PMID 37505794, PMID 38236249, PMID 38407630, PMID 38737792, PMID 38934093, PMID 38954785, PMID 39415930, PMID 39673591, PMID 40226119, PMID 40721981, PMID 41133726, PMID 41206673, PMID 41662628, PMID 42518206, PMID 42847673
UM1CA186689 (9), UM1CA186690 (7), UM1CA186712 (7), UM1CA186717 (7), UM1CA186644 (5), UM1CA186709 (5), U01CA062490 (4), UM1CA186688 (4), UM1CA186691 (4), UM1CA186704 (4), P30CA033572 (3), U01CA076576 (3), UM1CA186716 (3), P30CA006516 (2), P30CA016058 (2)