6 completed, 2 unknown, 2 withdrawn, 1 terminated. 5 Phase 2, 3 Phase 1, 2 Phase 3, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Unknown 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 2 | Completed 1, Withdrawn 1 |
| Not applicable | 1 | Terminated 1 |
| Phase 4 | 1 | Completed 1 |
Follow Collagenase: new trials by email Literature Review of Collagenase trials Research Report on Collagenase
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MEDIHONEY® Gel Versus Collagenase for Wound Debridement Active Leptospermum Honey (Medihoney), Collagenase - Ulcer, Wounds | Not applicable | Terminated | Integra LifeSciences Corporation | 10 | 2015-06-01 | 2017-12-02 |
| Evaluate the Noninferiority of Medicines Treating Uninfected Pressure Ulcers. Collagenase, Kollagenase - Pressure Ulcer | Phase 3 | Withdrawn | Cristália Produtos Químicos Farmacêuticos Ltda. | 2015-01-01 | 2015-07-16 | |
| Total Occlusion Study in Coronary Arteries - 5 collagenase, saline - Chronic Coronary Total Occlusions | Phase 2 | Completed | Matrizyme Pharma Corporation | 76 | 2014-04-01 | 2016-07-11 |
| Collagenase in the Treatment of Cellulite Collagenase, Biological - Cellulite | Phase 2 | Unknown | Stony Brook University | 20 | 2013-02-01 | 2012-12-12 |
| The Improvement of Limbal Epithelial Culture Technique by Using Collagenase to Isolate Limbal Stem Cells collagenase - Alkaline Chemical Burn Of Cornea And Conjunctival Sac, Acid Chemical Burn Of Cornea And Conjunctival Sac | Phase 1 | Unknown | National Taiwan University Hospital | 10 | 2012-01-01 | 2014-07-29 |
| MRI Results in Dupuytren's Contracture Before and After Injection With Xiaflex XIAFLEX - Dupuytren's Disease | Phase 4 | Completed | Hospital for Special Surgery, New York | 5 | 2011-03-01 | 2017-04-17 |
| Collagenase Total Occlusion-1 Trial collagenase - Chronic Total Occlusions | Phase 1 | Completed | Sunnybrook Health Sciences Centre | 28 | 2009-11-01 | 2012-03-23 |
| Collagenase in the Treatment of Adhesive Capsulitis (Frozen Shoulder) Collagenase - Adhesive Capsulitis, Frozen Shoulder | Phase 2 | Withdrawn | Stony Brook University | 2006-01-01 | 2019-10-03 | |
| Collagenase in the Treatment of Zone II Flexor Tendon Adhesions in the Hand Collagenase, Collagenase injection - Adhesion of Flexor Tendon of Hand | Phase 1 / Phase 2 | Completed | Stony Brook University | 3 | 2005-01-01 | 2016-04-21 |
| Phase II Randomized Study of Collagenase in Patients With Residual Type Dupuytren's Disease collagenase - Dupuytren's Contracture | Phase 2 | Completed | State University of New York | 36 | 1995-08-01 | 2015-03-25 |
| Phase III Randomized Study of Collagenase in Patients With Residual Stage Dupuytren's Disease collagenase - Dupuytren's Contracture | Phase 3 | Completed | State University of New York | 72 | 2015-03-25 |
Dupuytren Contracture (3) · Arthritis (2) · Connective Tissue Diseases (2) · Rare Diseases (2) · Bursitis (1) · Cellulite (1) · Pressure Ulcer (1) · Ulcer (1) · Wounds and Injuries (1)
Stony Brook University (3) · State University of New York (2) · Cristália Produtos Químicos Farmacêuticos Ltda. (1) · Hospital for Special Surgery, New York (1) · Integra LifeSciences Corporation (1) · Matrizyme Pharma Corporation (1) · National Taiwan University Hospital (1) · Sunnybrook Health Sciences Centre (1)
United States (6) · Canada (2) · Brazil (1) · Israel (1) · Netherlands (1) · Taiwan (1)
Marie A Badalamente, PhD (3) · Lawrence C. Hurst (2) · Alexander B Dagum, MD (1) · Bradley Strauss, MD, PhD, FRCP(C) (1) · Christopher Buller, Dr. (1) · Edward Wang, MD (1) · Norton Marcos S. Castro, Medic (1) · Ravi Patel, MD (1) · Scott W Wolfe, MD (1) · Wei Li Chen, MD, PhD (1)