19 completed, 1 not yet recruiting, 1 recruiting, 1 terminated. 13 Phase 4, 6 Phase 3, 3 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Completed 13 |
| Phase 3 | 6 | Completed 4, Not yet recruiting 1, Recruiting 1 |
| Not applicable | 3 | Completed 2, Terminated 1 |
Follow Colgate Cavity Protection Toothpaste: new trials by email Literature Review of Colgate Cavity Protection Toothpaste trials Research Report on Colgate Cavity Protection Toothpaste
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems 0.45% SnF HW with NaF (1450 F), 67% Bicarbonate with NaF (1400 F), Colgate Cavity Protection Toothpaste - Plaque, Dental Plaque | Phase 3 | Recruiting | Colgate Palmolive | 120 | 2026-07-20 | 2026-09-25 |
| Clinical Investigation of Oral Malodor for Max Fresh Toothpaste Containing Zinc Citrate Versus a Commercially Available Regular Fluoride Toothpaste Max Fresh Toothpaste, Colgate Cavity Protection Toothpaste - Oral Malodor | Phase 3 | Completed | Colgate Palmolive | 80 | 2026-06-12 | 2026-10-20 |
| Efficacy of a Toothpaste in Reducing Plaque, Gingivitis, and Gingival Bleeding Toothpaste containing chitosan, Colgate Cavity Protection Toothpaste - Plaque, Dental, Gingivitis | Phase 3 | Not yet recruiting | Colgate Palmolive | 90 | 2026-04-01 | 2026-04-13 |
| A Clinical Study Investigating the Efficacy of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health Test Fluoride Toothpaste, Colgate Cavity Protection Toothpaste - Dental Plaque, Gingivitis | Not applicable | Completed | HALEON | 154 | 2025-09-09 | 2026-01-21 |
| To Assess the Efficacy of a Toothpaste Containing 8% Arginine as Compared to Colgate Cavity Protection Toothpaste in the Reduction of Dentinal Hypersensitivity. TOMs of Maine Sensitive SLS Free Xtra Fresh, Colgate Cavity protection toothpaste - Sensitivity, Tooth | Phase 3 | Completed | Colgate Palmolive | 84 | 2025-08-18 | 2025-11-05 |
| Oothpaste Containing 8% Arginine Compared to Colgate Cavity Protection Toothpaste in Reducing Dentinal Hypersensitivity Toothpaste containing 8% Arginine, Colgate Cavity Protection Toothpaste - Hypersensitivity | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-07-14 | 2025-12-05 |
| A Clinical Study Investigating the Effect of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health Test toothpaste, Colgate Cavity Protection Toothpaste - Dental Plaque, Gingivitis | Not applicable | Completed | HALEON | 175 | 2024-09-23 | 2026-01-22 |
| The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis. Stannous fluoride toothpaste, Colgate Cavity Protection Toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 95 | 2024-04-22 | 2026-03-19 |
| A Study to Investigate Salivary Flow and Potential of Hydrogen (pH) Following Use of Essential-Oil Containing Mouthwashes Listerine Clinical Solutions Teeth Strength, Listerine Total Care Zero Alcohol Mouthwash, Listerine Cool Mint Zero Alcohol Mouthwash - Healthy | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 164 | 2023-11-13 | 2024-01-03 |
| A Two-Week Study of an Anticavity Low pH Mouthwash Listerine Experimental Mouthwash, Colgate Cavity Protection Toothpaste, Listerine Total Care Zero - Healthy | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 163 | 2023-07-17 | 2024-01-12 |
| A Study of Virtually Supervised Mouthwash and Interdental Brushes Colgate Cavity Protection Toothpaste, LISTERINE ZERO Alcohol Mouthwash COOL MINT, LISTERINE COOL MINT Antiseptic Mouthwash - Healthy | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 292 | 2023-02-09 | 2023-10-17 |
| A Two-Week Study of Clinical Safety and Saliva Flow Quantification Colgate Cavity Protection Toothpaste, LISTERINE Cool Mint Antiseptic Mouthwash, Listerine Advanced Gum Alcohol - Healthy | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 270 | 2022-11-28 | 2023-10-10 |
| A Twelve Week Study of Prototypes Mouth Rinses Colgate Cavity Protection Toothpaste, Zero Alcohol Gum Prototype, Alcohol Gum Prototype - Healthy | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 192 | 2022-08-31 | 2023-09-05 |
| A Study of Virtually Supervised Mouth Rinses and Flossing LISTERINE COOL MINT Antiseptic Mouthwash, LISTERINE COOL MINT ZERO Alcohol Mouthwash, Reach Unflavored Waxed Dental Floss - Healthy | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 284 | 2022-04-18 | 2023-06-18 |
| A Twelve Week Study of Experimental Mouth Rinses Colgate Cavity Protection Toothpaste, American Dental Association (ADA) Ref Toothbrush, Prototype 1 Mouth Rinse - Gingivitis, Plaque | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 300 | 2021-03-29 | 2023-06-29 |
| A Twelve Week Study of Virtually Supervised Mouth Rinse and Flossing Listerine Cool Mint, Colgate Cavity Protection Toothpaste, Reach Unflavored Waxed Dental Floss - Healthy | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 209 | 2020-10-23 | 2022-02-16 |
| 3M Oral Rinse Incidence and Patient Acceptance of Sloughing When Used With Sodium Lauryl Sulfate (SLS) Toothpastes No SLS toothpaste, Medium SLS toothpaste, High SLS toothpaste - Oral Mucosal Disorder | Not applicable | Terminated | Solventum US LLC | 53 | 2020-01-06 | 2024-10-01 |
| A Study of Mouth Rinses in Type 1 and Type 2 Diabetic Participants Listerine Cool Mint, 5% Hydroalcohol Mouth Rinse, Colgate Cavity Protection Toothpaste - Gingivits in Diabetics | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 154 | 2019-12-02 | 2023-08-07 |
| Clinical Investigation of a Toothpaste Containing Stannous Fluoride as Compared to Colgate Fluoride Toothpaste Colgate Total SF, Colgate Cavity Protection toothpaste - Gingivitis | Phase 4 | Completed | Colgate Palmolive | 88 | 2019-03-06 | 2022-09-27 |
| A Twelve Week Study of Supervised Mouth Rinse and Flossing Colgate Cavity Protection Toothpaste, American Dental Association (ADA) Referenced Toothbrush, 5% Hydroalcohol Mouth Rinse - Healthy | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 149 | 2018-09-26 | 2021-09-28 |
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Gingivitis (9) · Dental Plaque (5) · Plaque, Amyloid (3) · Dentin Sensitivity (1) · Hypersensitivity (1)
Johnson & Johnson Consumer Inc. (J&JCI) (10) · Colgate Palmolive (9) · HALEON (2) · Solventum US LLC (1)
United States (14) · Canada (2) · China (2) · Thailand (2) · Italy (1) · United Kingdom (1)
Jeffery Milleman, DDS (8) · Terdphong Triratana (2) · Brenda C Coalwell, BA (1) · Chhaju Ram Goyal, DDS (1) · David Paquette, DMD (1) · Deyu Hu (1) · Farid Ayad (1) · Jeffery Milleman (1) · Luigi Montensani, DDS (1) · Yiming LI, DDS, PhD (1) · Yun Po Zhang, Doctoral (1)