3 not yet recruiting, 3 unknown, 1 recruiting, 1 terminated. 3 Phase 2, 2 Phase 3, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Not yet recruiting 2, Unknown 1 |
| Phase 3 | 2 | Recruiting 1, Terminated 1 |
| Not applicable | 1 | Unknown 1 |
Follow brain radiotherapy: new trials by email Literature Review of brain radiotherapy trials Research Report on brain radiotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sacituzumab Tirumotecan（Sac-TMT） and Brain Radotherapy for EGFR+ NSCLC With Brain Mets brain radiotherapy, Sacituzumab Tirumotecan (Sac-TMT) - Non-Small Cell Lung Cancer, Brain Metastases From Non-small Cell Lung Cancer (NSCLC) | Phase 2 | Not yet recruiting | Xiaorong Dong | 53 | 2026-08-30 | 2026-08-27 |
| Impact of Radiotherapy-Immunotherapy Timing in NSCLC Brain Metastases Brain radiotherapy - Non Small Cell Lung, Brain Metastasases | Not yet recruiting | Xiangya Hospital of Central South University | 150 | 2026-06-05 | 2026-06-10 | |
| Brain Radiotherapy Combined With Dalpiciclib and Endocrine Therapy in HR-Positive/HER2-Negative Advanced Breast Cancer With Brain Metastases Dalpiciclib, Endocrine Therapy of Physician's Choice, Brain Radiotherapy - Breast Cancer, Brain Metastases | Phase 2 | Not yet recruiting | Nanfang Hospital, Southern Medical University | 46 | 2026-06-01 | 2026-04-30 |
| Clinical Feasibility of Brain Radiotherapy Using Synthetic CTs in an MRI-only Workflow brain radiotherapy - Brain Tumor, Primary, Brain Tumor - Metastatic | Not applicable | Unknown | University of Erlangen-Nürnberg Medical School | 54 | 2024-01-01 | 2023-10-30 |
| Early or Delayed Intervention of Brain Radiotherapy Combined With Almonertinib in EGFR Mutated NSCLC With Brain Metastases brain radiotherapy, Almonertinib - Brain Metastases, Radiotherapy | Phase 3 | Recruiting | Sun Yat-sen University | 232 | 2023-03-15 | 2023-03-14 |
| The Role of Brain Radiotherapy in Patients With Asymptomatic Brain Metastasis in the Era of Targeted Therapy for NSCLC molecular targeted therapies, Brain Radiotherapy - Non Small Cell Lung Cancer, Brain Metastases | Phase 2 | Unknown | Second Affiliated Hospital of Nanchang University | 100 | 2019-12-01 | 2019-12-10 |
| Study of Neurological Complication After Radiotherapy for High Grade Glioblastoma brain radiotherapy - Leukoencephalopathy | Unknown | Sophie JACOB | 200 | 2015-04-01 | 2016-09-22 | |
| Therapeutic Strategies in Patients With Non-squamous Non-small Cell Lung Cancer With Brain Metastases Cisplatin, Pemetrexed, Bevacizumab - Non-small Cell Lung Cancer Metastatic, Non-small Cell Lung Cancer | Phase 3 | Terminated | Centre Hospitalier Intercommunal Creteil | 95 | 2013-12-01 | 2019-02-01 |
Brain Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (3) · Breast Neoplasms (1) · Leukoencephalopathies (1)
Centre Hospitalier Intercommunal Creteil (1) · Nanfang Hospital, Southern Medical University (1) · Second Affiliated Hospital of Nanchang University (1) · Sophie JACOB (1) · Sun Yat-sen University (1) · University of Erlangen-Nürnberg Medical School (1) · Xiangya Hospital of Central South University (1) · Xiaorong Dong (1)
China (4) · France (2) · Germany (1)
Christoph Bert, Prof. Dr. rer. nat (1) · Florian Putz, PD Dr. med. (1) · Likun Chen (1) · Liu Anwen, Phd (1)
PMID 11452123, PMID 12750523, PMID 16757720, PMID 17229875, PMID 19801201, PMID 21041710, PMID 21472002, PMID 22012633, PMID 22134072, PMID 23129122, PMID 24021541, PMID 24419416, PMID 26148750, PMID 26684198, PMID 26823294, PMID 27343440, PMID 27458945, PMID 28126333, PMID 33948123, PMID 38459584