2 recruiting, 1 completed, 1 not yet recruiting, 1 withdrawn. 2 Phase 3, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Recruiting 2 |
| Phase 4 | 2 | Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
Follow apraclonidine: new trials by email Literature Review of apraclonidine trials Research Report on apraclonidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Iopidine to Decrease Intraocular Pressure Rise After Injections Apraclonidine 1.0% ophthalmic solution - Macular Degeneration, Diabetic Retinopathy | Phase 4 | Not yet recruiting | Retina Consultants of Delmarva | 120 | 2026-10-01 | 2026-10-23 |
| Efficacy and Safety of FID 123472 Ophthalmic Solution for Ocular Redness in Adults Apraclonidine Ophthalmic Solution, 0.125% Unit Dose Preservative Free, Vehicle - Ocular Hyperemia | Phase 3 | Recruiting | Alcon Research | 230 | 2026-09-30 | 2026-10-16 |
| An Investigation of FID 123472 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness in Adults Apraclonidine Ophthalmic Solution, 0.125% Unit Dose Preservative Free, Vehicle - Ocular Hyperemia | Phase 3 | Recruiting | Alcon Research | 178 | 2026-09-27 | 2026-10-16 |
| Efficacy of Topical Apraclonidine for the Treatment of Ocular Synkinesis Apraclonidine - Synkinesis, Facial Nerve Palsy | Phase 4 | Withdrawn | University of Alabama at Birmingham | 2025-12-01 | 2024-07-19 | |
| Efficacy of Apraclonidine Eye Drops in the Treatment of Ptosis Secondary to Myasthenia Gravis Apraclonidine Hcl 0.5% Oph Soln - Myasthenia Gravis, Ocular Myasthenia Gravis | Phase 2 | Completed | American University of Beirut Medical Center | 10 | 2020-06-01 | 2021-09-16 |
Bell Palsy (1) · Diabetic Retinopathy (1) · Glaucoma (1) · Macular Degeneration (1) · Myasthenia Gravis (1) · Retinal Vein Occlusion (1) · Synkinesis (1)
Alcon Research (2) · American University of Beirut Medical Center (1) · Retina Consultants of Delmarva (1) · University of Alabama at Birmingham (1)
United States (3) · Lebanon (1)
Benjamin Greene, MD (1) · Johnny Salameh, MD (1)