5 completed, 1 not yet recruiting, 1 terminated. 5 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 4, Not yet recruiting 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
Follow afabicin: new trials by email Literature Review of afabicin trials Research Report on afabicin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Renal Impairment Pharmacokinetics (PK) Trial of Afabicin Afabicin Oral, Afabicin IV - Renal Impairment | Phase 1 | Not yet recruiting | Debiopharm International SA | 60 | 2026-09-01 | 2026-09-22 |
| Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus Afabicin, Cefazolin, Vancomycin - Bone or Joint Infection | Phase 2 | Terminated | Debiopharm International SA | 67 | 2019-02-20 | 2026-09-09 |
| A Study to Investigate the Effect of Itraconazole on the Pharmacokinetics of Debio 1450 in Healthy Subjects Debio 1450, Itraconazole - Healthy Participants | Phase 1 | Completed | Debiopharm International SA | 20 | 2017-06-14 | 2017-10-18 |
| Drug Penetration Into Bone After Repeated Oral Administration of Debio 1450 to Patients Undergoing Hip Replacement Surgery Debio 1450 - Bone Diseases, Infectious | Phase 1 | Completed | Debiopharm International SA | 17 | 2016-04-01 | 2017-10-18 |
| Study of Debio 1450 for Bacterial Skin Infections Debio 1450 IV, Debio 1450 Oral, Linezolid - Bacterial Infections | Phase 2 | Completed | Debiopharm International SA | 330 | 2015-05-01 | 2019-11-13 |
| A Multiple Dose Study of Debio 1450 [Intravenous (IV) and Oral] in Healthy Volunteers Placebo IV Solution, Debio 1450 IV Solution, Placebo Tablet or Capsule - Bacterial Infections | Phase 1 | Completed | Debiopharm International SA | 70 | 2014-08-01 | 2015-02-25 |
| A Single Dose Study of Debio 1450 in Healthy Subjects Debio 1450, Placebo - Bacterial Infections | Phase 1 | Completed | Debiopharm International SA | 48 | 2014-06-01 | 2014-10-23 |
Bacterial Infections (3) · Bone Diseases, Infectious (1) · Renal Insufficiency (1)
Debiopharm International SA (7)
United States (4) · Georgia (1) · Germany (1) · South Africa (1) · Ukraine (1) · United Kingdom (1)
Azra Hussaini, MD (1) · Frederick Wittke, MD (1)
2017 (1)