2 suspended, 1 not yet recruiting, 1 recruiting. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Suspended 2, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Actinium: new trials by email Literature Review of Actinium trials Research Report on Actinium
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma Actinium Ac 225 Lintuzumab, Biospecimen Collection, Cemiplimab - Recurrent Glioblastoma, IDH-Wildtype, Recurrent Gliosarcoma | Phase 1 | Not yet recruiting | National Cancer Institute (NCI) | 30 | 2026-12-04 | 2026-06-12 |
| Testing the Combination of Targeted Radiotherapy With Anti-Cancer Drugs, Venetoclax and ASTX-727, to Improve Outcomes for Adults With Newly Diagnosed Acute Myeloid Leukemia Actinium Ac 225 Lintuzumab, Biospecimen Collection, Bone Marrow Aspiration - Acute Myeloid Leukemia | Phase 1 | Suspended | National Cancer Institute (NCI) | 53 | 2026-11-18 | 2026-08-24 |
| Testing an Anti-cancer Radio-Active Immunotherapy Called Lintuzumab Ac225 in Patients With High-Risk Myelodysplastic Syndrome That Has Not Responded to Other Treatment Actinium Ac 225 Lintuzumab, Bone Marrow Aspiration, Buccal Swab - Refractory Myelodysplastic Syndrome | Phase 1 | Suspended | National Cancer Institute (NCI) | 18 | 2026-09-03 | 2026-09-09 |
| ACTinium in Castrate-RESistant Prostate Cancer After LUTEtium Actinium (225Ac) rhPSMA-10.1 - Metastatic Castration-resistant Prostate Cancer, Metastatic Prostate Cancer | Phase 1 / Phase 2 | Recruiting | University College, London | 60 | 2026-04-13 | 2026-05-08 |
Glioblastoma (1) · Gliosarcoma (1) · Leukemia, Myeloid, Acute (1) · Myelodysplastic Syndromes (1) · Prostatic Neoplasms (1)
National Cancer Institute (NCI) (3) · University College, London (1)
United States (2) · United Kingdom (1)
Gerhardt Attard (1) · Manu Pandey (1) · Megan Mantica (1) · Talha Badar (1)
UM1CA186689 (1), UM1CA186690 (1), UM1CA186709 (1)