4 recruiting, 3 completed, 2 withdrawn, 1 active not recruiting. 5 Phase 2, 3 Phase 1, 1 Early Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Withdrawn 2, Active not recruiting 1, Completed 1, Recruiting 1 |
| Phase 1 | 3 | Active not recruiting 1, Completed 1, Terminated 1 |
| Early Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow 3-fluorobenzylguanidine: new trials by email Literature Review of 3-fluorobenzylguanidine trials Research Report on 3-fluorobenzylguanidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing 123I-MIBG and 18F-MFBG Imaging in Patients With Newly Diagnosed, High Risk Neuroblastoma Biospecimen Collection, Computed Tomography, Florbenguane F18 - Ganglioneuroblastoma, Ganglioneuroblastoma, Nodular | Phase 2 | Withdrawn | Children's Oncology Group | 2026-09-22 | 2026-09-16 | |
| A Prospective Image Reevaluation Study to Assess the Efficacy of 18F-mFBG PET Imaging in Subjects With Neuroblastoma 18F-MFBG - Neuroblastoma | Completed | Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) | 43 | 2026-06-01 | 2026-09-22 | |
| 18F-mFBG Cardiac Uptake With Lewy Body Dementia 18F-MFBG - Parkinson Disease (PD), Lewy Body Dementia (LBD) | Phase 2 | Recruiting | Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) | 20 | 2026-04-30 | 2026-07-01 |
| 18F-mFBG PET Imaging in the Evaluation of Neuroblastoma 18F-MFBG - Neuroblastoma | Recruiting | First Affiliated Hospital of Zhejiang University | 200 | 2025-02-04 | 2025-08-08 | |
| 18F-mFBG Expression in Neural Crest Tumors and Organs Innervated by the Sympathetic Nervous System 18F-mFBG - Neuroblastoma, Pheochromocytoma | Phase 2 | Withdrawn | Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) | 2025-01-01 | 2025-01-21 | |
| 18F-mFBG PET Imaging in the Evaluation of Pheochromocytoma 18F-MFBG - Pheochromocytoma | Recruiting | First Affiliated Hospital of Zhejiang University | 80 | 2023-05-01 | 2025-08-07 | |
| Open-Label Study of 18F-mFBG for Imaging Neuroblastoma 18F-MFBG - Neuroblastoma | Phase 3 | Completed | Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) | 43 | 2021-11-18 | 2026-09-29 |
| Open-Label Study of 18F-mFBG for Imaging Myocardial Sympathetic Innervation 18F-mFBG for intravenous administration - Cardiovascular Diseases | Phase 1 / Phase 2 | Active not recruiting | Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) | 10 | 2021-11-05 | 2026-07-02 |
| 18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor 18F-MFBG, 68Ga-Dotatate - Neuroendocrine Tumor, Neuroblastoma | Early Phase 1 | Recruiting | Peking Union Medical College Hospital | 150 | 2021-09-01 | 2024-03-01 |
| 18F-MFBG PET Imaging of the Norepinephrine Transporter in Neural Crest and Neuroendocrine Tumors (18F)MFBG, PET/CT, Venous blood samples - Neural Crest Tumor, Neuroendocrine Tumors | Phase 1 | Terminated | Universitaire Ziekenhuizen KU Leuven | 6 | 2020-02-07 | 2022-08-12 |
| 18F-MFBG Imaging for Evaluation of Neuroendocrine Malignancies 18F-MFBG (meta-fluoro benzylguanidine), Positron emission tomography (PET) imaging, Blood draws - Neuroendocrine Tumors | Phase 1 / Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 48 | 2015-01-01 | 2025-03-19 |
Neuroblastoma (5) · Neuroendocrine Tumors (3) · Pheochromocytoma (3) · Paraganglioma (2) · Cardiovascular Diseases (1) · Ganglioneuroblastoma (1) · Lewy Body Disease (1) · Neural crest tumor (1) · Parkinson Disease (1)
Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) (5) · First Affiliated Hospital of Zhejiang University (2) · Children's Oncology Group (1) · Memorial Sloan Kettering Cancer Center (1) · Peking Union Medical College Hospital (1) · Universitaire Ziekenhuizen KU Leuven (1)
United States (6) · China (3) · Belgium (1)
Alice Lee, MD (1) · Arnold F Jacobson, MD PhD (1) · Arnold F Jacobson, MD, PhD (1) · Christophe Deroose, MD, PhD (1) · Fang Li (1) · Juan B Toledo, MD (1) · Neeta Pandit-Taskar, MD (1) · Tanya C Watt (1) · Vikram Agarwal, MD (1)
PMID 32385645, PMID 36435928, PMID 37160439, PMID 40717185
UM1CA228823 (1)