TP53 Gene Mutation: Clinical Trials

1 not yet recruiting. 1 Phase 1.

By phase and status

Phase	Trials	Status
Phase 1	1	Not yet recruiting 1

Follow TP53 Gene Mutation: new trials by email Literature Review of TP53 Gene Mutation trials Research Report on TP53 Gene Mutation

Trials (filtered) newest first · largest first

All 1 trial

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Axatilimab Combined With Decitabine/Venetoclax for the Treatment of TP53-mutated AML Decitabine, Venetoclax, Axatilimab - Acute Myeloid Leukemia, TP53 Gene Mutation	Phase 1	Not yet recruiting	Northside Hospital, Inc.	32	2027-01-31	2026-10-16

Narrower conditions

Leukemia, Myeloid, Acute (1)

Broader conditions

Hematologic Diseases (1)  ·  Hemic and Lymphatic Diseases (1)  ·  Leukemia (1)  ·  Leukemia, Myeloid (1)  ·  Neoplasms (1)  ·  Neoplasms by Histologic Type (1)

Interventions

Decitabine (1)  ·  axatilimab (1)  ·  venetoclax (1)

Sponsors

Northside Hospital, Inc. (1)

Countries

United States (1)

Results publications

PMID 20602996, PMID 20876310, PMID 21654748, PMID 23733335, PMID 24639350, PMID 25047706, PMID 25157821, PMID 25484881, PMID 26358057, PMID 28126925, PMID 28212753, PMID 29632729, PMID 30425048, PMID 31940491, PMID 32002295, PMID 32499238, PMID 32605996, PMID 32730593, PMID 33057635, PMID 33415170, PMID 34249942, PMID 34255353, PMID 34298810, PMID 34771453, PMID 35030341, PMID 35965420, PMID 36226545, PMID 36459673, PMID 36549780, PMID 37370821, PMID 39133921, PMID 39292927, PMID 39457618, PMID 7506935