Refractory Nodal Marginal Zone Lymphoma: Clinical Trials

7 trials for Refractory Nodal Marginal Zone Lymphoma, newest first

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2 recruiting, 2 withdrawn, 1 completed, 1 not yet recruiting. 4 Phase 1, 3 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 14Withdrawn 2, Recruiting 1, Terminated 1
Phase 23Completed 1, Not yet recruiting 1, Recruiting 1

Follow Refractory Nodal Marginal Zone Lymphoma: new trials by email Literature Review of Refractory Nodal Marginal Zone Lymphoma trials Research Report on Refractory Nodal Marginal Zone Lymphoma

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Testing Mosunetuzumab Alone, With Zanubrutinib, or With Polatuzumab Vedotin for Treating Marginal Zone Lymphoma That Came Back or Didn't Get Better With Treatment
Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography - Recurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue, Recurrent Nodal Marginal Zone Lymphoma
Phase 2Not yet recruitingSWOG Cancer Research Network1382026-10-032026-10-13
Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Biopsy, Biospecimen Collection, Bone Marrow Aspiration - Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Phase 1RecruitingCity of Hope Medical Center372025-08-252026-04-20
Epcoritamab Plus Standard of Care Platinum-Based Chemotherapy and Autologous Hematopoietic Cell Transplant for the Treatment of Relapsed or Refractory Large B-cell Lymphoma
Autologous Hematopoietic Stem Cell Transplantation, Carboplatin, Cytarabine - Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Phase 2RecruitingUniversity of California, Davis252025-07-312026-06-30
Lenalidomide, Umbralisib, and Ublituximab for the Treatment of Relapsed or Refractory Indolent Non-Hodgkin Lymphoma or Mantle Cell Lymphoma
Lenalidomide, Ublituximab, Umbralisib - Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue
Phase 1WithdrawnYazeed Sawalha2022-09-302022-09-30
Acalabrutinib and Duvelisib for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin Lymphoma
Acalabrutinib, Duvelisib - Recurrent Follicular Lymphoma, Recurrent Marginal Zone Lymphoma
Phase 1WithdrawnNarendranath Epperla2022-07-012022-06-07
Direct Tumor Microinjection and FDG-PET in Testing Drug Sensitivity in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Stage IV Breast Cancer
Belinostat, Carfilzomib, Copanlisib Hydrochloride - Breast Adenocarcinoma, Metastatic Breast Carcinoma
Phase 1TerminatedMayo Clinic172018-03-272025-05-26
Pembrolizumab Alone or With Idelalisib or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Non-Hodgkin Lymphomas
Ibrutinib, Idelalisib, Laboratory Biomarker Analysis - Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Chronic Lymphocytic Leukemia
Phase 2CompletedMayo Clinic652015-02-192026-06-24

Narrower conditions

Lymphoma, B-Cell, Marginal Zone (7)  ·  Lymphoma, Follicular (4)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (2)  ·  Lymphoma, B-Cell (2)  ·  Lymphoma, Large B-Cell, Diffuse (2)  ·  Lymphoma, Mantle-Cell (2)  ·  Waldenstrom Macroglobulinemia (2)  ·  Breast Neoplasms (1)  ·  Hodgkin Disease (1)  ·  Lymphoma, Non-Hodgkin (1)  ·  Lymphoma, T-Cell, Cutaneous (1)  ·  Mycosis Fungoides (1)

Broader conditions

Hemic and Lymphatic Diseases (7)  ·  Immune System Diseases (7)  ·  Immunoproliferative Disorders (7)  ·  Lymphatic Diseases (7)  ·  Lymphoma (7)  ·  Lymphoproliferative Disorders (7)  ·  Neoplasms (7)  ·  Neoplasms by Histologic Type (7)  ·  Lymphoma, Non-Hodgkin (6)  ·  Lymphoma, B-Cell (5)  ·  Hematologic Diseases (3)  ·  Blood Protein Disorders (2)  ·  Cardiovascular Diseases (2)  ·  Chronic Disease (2)  ·  Disease Attributes (2)

Interventions

Magnetic Resonance Spectroscopy (3)  ·  Biopsy (2)  ·  CT-P10 (2)  ·  Gemcitabine (2)  ·  Rituximab (2)  ·  Specimen Handling (2)  ·  pembrolizumab (2)  ·  zanubrutinib (2)  ·  Calcium Dobesilate (1)  ·  Carboplatin (1)  ·  Cytarabine (1)  ·  Depsipeptides (1)  ·  Dexamethasone (1)  ·  Fluorodeoxyglucose F18 (1)  ·  Ifosfamide (1)

Sponsors

Mayo Clinic (2)  ·  City of Hope Medical Center (1)  ·  Narendranath Epperla (1)  ·  SWOG Cancer Research Network (1)  ·  University of California, Davis (1)  ·  Yazeed Sawalha (1)

Countries

United States (5)

Top investigators

Boyu Hu (1)  ·  Geoffrey Shouse (1)  ·  Grzegorz S. Nowakowski, M.D. (1)  ·  Joseph M Tuscano (1)  ·  Narendranath Epperla, MD (1)  ·  Wei Ding (1)  ·  Yazeed Sawalha, MD (1)

Results publications

PMID 28424162

NIH funding

P30CA033572 (1), P30CA093373 (1), P50CA097274 (1), U10CA180888 (1)