2 not yet recruiting, 1 recruiting, 1 suspended. 4 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Not yet recruiting 2, Recruiting 1, Suspended 1 |
| Phase 2 | 3 | Not yet recruiting 2, Suspended 1 |
Follow Recurrent Childhood Malignant Solid Neoplasm: new trials by email Literature Review of Recurrent Childhood Malignant Solid Neoplasm trials Research Report on Recurrent Childhood Malignant Solid Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1/2 Study of CBX-12 in Children, Adolescents, or Young Adults With Solid Tumors That Have Come Back After Treatment or Are Difficult to Treat Archive Sample Retrieval, Biospecimen Collection, pH Low Insertion Peptide-exatecan Conjugate CBX-12 - Recurrent Childhood Ewing Sarcoma, Recurrent Childhood Malignant Solid Neoplasm | Phase 1 / Phase 2 | Not yet recruiting | Children's Oncology Group | 79 | 2027-05-07 | 2026-09-22 |
| Testing the Addition of an Anti-Cancer Drug, Daraxonrasib, for Relapsed or Refractory Solid Tumors With RAS Mutations Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Childhood Malignant Solid Neoplasm, Recurrent Childhood Neuroblastoma | Phase 1 / Phase 2 | Not yet recruiting | Children's Oncology Group | 77 | 2027-04-09 | 2026-09-15 |
| Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma Bcl-XL Proteolysis Targeting Chimera DT2216, Biospecimen Collection, Irinotecan - Childhood Fibrolamellar Carcinoma, Recurrent Childhood Fibrolamellar Carcinoma | Phase 1 / Phase 2 | Suspended | Children's Oncology Group | 81 | 2025-06-12 | 2026-08-24 |
| Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling Functional Precision Medicine - Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia | Phase 1 | Recruiting | Florida International University | 65 | 2023-02-22 | 2026-08-26 |
Dendritic Cell Sarcoma, Interdigitating (1) · Familial ependymoma (1) · Fibrolamellar hepatocellular carcinoma (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Neoplasms (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Rhabdomyosarcoma (1) · Sarcoma, Ewing (1)
Neoplasms by Histologic Type (2) · Bone Marrow Diseases (1) · Chronic Disease (1) · Disease Attributes (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Histiocytic Disorders, Malignant (1) · Histiocytosis (1) · Immune System Diseases (1) · Immunoproliferative Disorders (1) · Leukemia (1) · Leukemia, Lymphoid (1) · Leukemia, Myeloid (1) · Lymphatic Diseases (1) · Lymphoproliferative Disorders (1)
Specimen Handling (3) · Biopsy (1) · DT2216 (1) · Irinotecan (1) · Phantoms, Imaging (1) · X-Rays (1)
Children's Oncology Group (3) · Florida International University (1)
United States (2)
Amit J Sabnis (1) · Diana Azzam (1) · Juan C Vasquez (1) · Maggie Fader (1) · Michael V Ortiz (1)
UM1CA228823 (3), U54MD012393 (1)