2 active not recruiting, 1 completed, 1 not yet recruiting, 1 withdrawn. 3 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Active not recruiting 1, Completed 1, Not yet recruiting 1 |
| Phase 2 | 3 | Active not recruiting 2, Withdrawn 1 |
Follow Recurrent B Lymphoblastic Lymphoma: new trials by email Literature Review of Recurrent B Lymphoblastic Lymphoma trials Research Report on Recurrent B Lymphoblastic Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma Autologous BAFFR-targeting CAR T Cells, Biospecimen Collection, Bone Marrow Aspiration - Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma | Phase 1 | Not yet recruiting | City of Hope Medical Center | 16 | 2027-04-17 | 2026-08-11 |
| Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Recurrent or Refractory B-cell Acute Lymphoblastic Leukemia Etoposide, Doxorubicin, Vincristine - Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma | Phase 1 | Completed | University of Washington | 24 | 2019-09-24 | 2023-07-06 |
| Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia Biospecimen Collection, Computed Tomography, Lumbar Puncture - Recurrent Adult Lymphoblastic Lymphoma, Recurrent B Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | Active not recruiting | ECOG-ACRIN Cancer Research Group | 40 | 2018-08-13 | 2026-10-06 |
| Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride With Asparaginase in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Asparaginase, Cyclophosphamide, Doxorubicin Hydrochloride - B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma | Phase 2 | Withdrawn | University of Washington | 2018-07-01 | 2018-11-14 | |
| Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Bone Marrow Aspiration and Biopsy - Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma | Phase 2 | Active not recruiting | Children's Oncology Group | 80 | 2017-06-19 | 2026-10-01 |
Burkitt Lymphoma (5) · Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (5) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (2) · Lymphoma (1)
DNA Virus Infections (5) · Epstein-Barr Virus Infections (5) · Hematologic Diseases (5) · Hemic and Lymphatic Diseases (5) · Herpesviridae Infections (5) · Immune System Diseases (5) · Immunoproliferative Disorders (5) · Infections (5) · Leukemia (5) · Leukemia, Lymphoid (5) · Lymphatic Diseases (5) · Lymphoma, B-Cell (5) · Lymphoma, Non-Hodgkin (5) · Lymphoproliferative Disorders (5) · Neoplasms (5)
Cyclophosphamide (4) · Vincristine (4) · Specimen Handling (3) · Asparaginase (2) · Biopsy (2) · Doxorubicin (2) · Etoposide (2) · Inotuzumab Ozogamicin (2) · Magnetic Resonance Spectroscopy (2) · Prednisone (2) · Spinal Puncture (2) · X-Rays (2) · Bridge Therapy (1) · Cytarabine (1) · Imatinib Mesylate (1)
University of Washington (2) · Children's Oncology Group (1) · City of Hope Medical Center (1) · ECOG-ACRIN Cancer Research Group (1)
United States (5) · Puerto Rico (2)
Ryan Cassaday (2) · Ibrahim Aldoss (1) · Maureen M O'Brien (1) · Neil D Palmisiano (1)
PMID 35007127, PMID 35622074, PMID 38722664, PMID 39415930, PMID 41671463
P30CA015704 (1), P30CA033572 (1), U10CA180820 (1), U10CA180886 (1)