2 completed, 1 enrolling by invitation. 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Enrolling by invitation 1 |
| Phase 2 | 2 | Completed 1, Enrolling by invitation 1 |
Follow Progeria: new trials by email Literature Review of Progeria trials Research Report on Progeria
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I Study of Progerinin in Healthy Volunteers Progerinin, Placebo - Hutchinson-Gilford Progeria Syndrome, Werner Syndrome | Phase 1 | Completed | PRG Science & Technology Co., Ltd. | 64 | 2020-08-24 | 2021-09-22 |
| Umbilical Cord Blood Transfusion in Progeria Syndrome Umbilical Cord Blood Unit - Hutchinson-Gilford Progeria Syndrome | Phase 1 / Phase 2 | Completed | Bundang CHA Hospital | 2 | 2019-03-05 | 2020-11-04 |
| Phase I/II Trial of Everolimus in Combination With Lonafarnib in Progeria Everolimus and lonafarnib - Progeria | Phase 1 / Phase 2 | Enrolling by invitation | Boston Children's Hospital | 80 | 2015-12-01 | 2026-04-02 |
Werner Syndrome (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Laminopathies (3) · Metabolic Diseases (3) · Metabolism, Inborn Errors (3) · Nutritional and Metabolic Diseases (3) · DNA Repair-Deficiency Disorders (1)
Everolimus (1) · Sirolimus (1) · lonafarnib (1)
Boston Children's Hospital (1) · Bundang CHA Hospital (1) · PRG Science & Technology Co., Ltd. (1)
United States (2) · South Korea (1)
Min Young Kim, MD, PhD (1) · Monica Kleinman, M.D. (1)