6 completed. 6 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 6 |
| Phase 3 | 3 | Completed 3 |
Follow Polycystic liver disease: new trials by email Literature Review of Polycystic liver disease trials Research Report on Polycystic liver disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease Ursodeoxycholic Acid - Polycystic Liver Disease, Polycystic Kidney, Autosomal Dominant | Phase 2 | Completed | Radboud University Medical Center | 34 | 2013-12-01 | 2021-09-23 |
| Pasireotide LAR in Severe Polycystic Liver Disease Pasireotide LAR, Placebo - Somatostatin Analogs, Polycystic Liver Disease | Phase 2 | Completed | Mayo Clinic | 48 | 2012-08-01 | 2020-05-01 |
| Lanreotide Autogel in the Treatment of Symptomatic Polycystic Liver Disease Lanreotide Autogel 90 mg and 120 mg - Polycystic Liver Disease | Phase 2 / Phase 3 | Completed | Universitaire Ziekenhuizen KU Leuven | 59 | 2011-03-01 | 2014-07-08 |
| Everolimus and LongActing Octreotide Trial in Polycystic Livers Everolimus, Octreotide LAR - Polycystic Liver Disease | Phase 2 | Completed | Radboud University Medical Center | 44 | 2010-06-01 | 2015-06-29 |
| Lanreotide as Treatment of Polycystic Livers Placebo, Lanreotide - Polycystic Liver Disease, Hepatomegaly | Phase 2 / Phase 3 | Completed | Radboud University Medical Center | 38 | 2007-10-01 | 2009-02-17 |
| Octreotide in Severe Polycystic Liver Disease Octreotide, Placebo - Polycystic Kidney, Autosomal Dominant, Polycystic Liver Disease | Phase 2 / Phase 3 | Completed | Mayo Clinic | 42 | 2007-01-01 | 2012-11-21 |
Polycystic Kidney, Autosomal Dominant (4) · Hepatomegaly (2) · Liver Diseases (2) · Abdominal Pain (1) · Polycystic Kidney Diseases (1)
Abnormalities, Multiple (4) · Ciliopathies (4) · Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Genetic Diseases, Inborn (4) · Kidney Diseases (4) · Kidney Diseases, Cystic (4) · Male Urogenital Diseases (4) · Urogenital Diseases (4) · Urologic Diseases (4) · Polycystic Kidney Diseases (3) · Digestive System Diseases (2) · Hypertrophy (2)
Everolimus (1) · Octreotide (1) · Ursodeoxycholic Acid (1) · lanreotide (1)
Radboud University Medical Center (3) · Mayo Clinic (2) · Universitaire Ziekenhuizen KU Leuven (1)
Netherlands (3) · Belgium (2) · United States (2) · Spain (1)
Frederik Nevens, MD, PhD (2) · Joost PH Drenth, MD, PhD (2) · Joost PH Drenth, dr. (1) · Loes van Keimpema, MSc (1) · Marie C Hogan, MD PhD (1) · Marie C. Hogan, M.D., Ph.D. (1) · Melissa Chrispijn, MD (1)
PMID 39356039, PMID 19646443, PMID 22104015, PMID 22773240, PMID 26073493, PMID 26166166, PMID 27212247, PMID 32843370
UL1RR024150 (1)