4 completed, 1 recruiting. 1 Phase 3.
By phase and status
Follow Non-squamous, Non-Small Cell Lung Cancer: new trials by email Literature Review of Non-squamous, Non-Small Cell Lung Cancer trials Research Report on Non-squamous, Non-Small Cell Lung Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
Aglatimagene Besadenovec + Prodrug and Pembrolizumab vs Docetaxel for Stage IV Non-Squamous NSCLC Progressing on Pembrolizumab (AURORA) Aglatimagene Besadenovec, Valacyclovir, Pembrolizumab - Non-squamous, Non-Small Cell Lung Cancer | Phase 3 | Recruiting | 500 | 2026-06-15 | 2026-06-22 |
Non-interventional Study for Real-world Data of Afatinib Treatment in First-line Setting and of Subsequent Therapies for Patients With Advanced Epidermal Growth Factor Receptor (EGFR) Mutation-positive Lung Adenocarcinoma afatinib - Non-squamous, Non-Small Cell Lung Cancer | | Completed | 805 | 2021-08-26 | 2024-12-27 |
Real-World Effectiveness of Afatinib (Gilotrif) Following Immunotherapy in the Treatment of Metastatic, Squamous Cell Carcinoma of the Lung: A Multi-Site Retrospective Chart Review Study in the U.S. Afatinib, other systemic therapy - Non-squamous, Non-Small Cell Lung Cancer | | Completed | 110 | 2020-10-15 | 2024-09-19 |
The Study Observes Afatinib as First-line Treatment in Patients With Epidermal Growth Factor Receptor (EGFR) Mutation-positive Advanced Non-small Cell Lung Cancer Afatinib - Non-squamous, Non-Small Cell Lung Cancer | | Completed | 72 | 2020-05-20 | 2025-02-28 |
The Study Observes How Long Patients With Non-small Cell Lung Cancer (NSCLC) Benefit From Treatment With Epidermal Growth Factor Tyrosine Kinase Inhibitor (EGFR-TKI) When Given Either for Uncommon Mutations or for Common Mutations in the Sequence Afatinib Followed by Osimertinib Afatinib (Gi(l)otrif®), Erlotinib (Tarceva®), Gefitinib (IRESSA®) - Non-squamous, Non-Small Cell Lung Cancer | | Completed | 462 | 2019-12-17 | 2023-05-25 |
Narrower conditions
Carcinoma, Non-Small-Cell Lung (5)
Broader conditions
Bronchial Neoplasms (5) · Carcinoma, Bronchogenic (5) · Lung Diseases (5) · Lung Neoplasms (5) · Neoplasms (5) · Neoplasms by Site (5) · Respiratory Tract Diseases (5) · Respiratory Tract Neoplasms (5) · Thoracic Neoplasms (5)
Interventions
Afatinib (4) · Docetaxel (1) · Erlotinib Hydrochloride (1) · Gefitinib (1) · Valacyclovir (1) · osimertinib (1) · pembrolizumab (1)
Sponsors
Boehringer Ingelheim (4) · Candel Therapeutics, Inc. (1)
Countries
United States (2) · China (1) · Japan (1) · United Kingdom (1)
Results publications
PMID 35274704, PMID 40483538