Narcolepsy With Cataplexy: Clinical Trials

4 completed. 4 Phase 3.

By phase and status

Phase	Trials	Status
Phase 3	4	Completed 4

Follow Narcolepsy With Cataplexy: new trials by email Literature Review of Narcolepsy With Cataplexy trials Research Report on Narcolepsy With Cataplexy

Trials (filtered) newest first · largest first

All 4 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
A Study of the Efficacy and Safety of JZP-258 in Subjects With Narcolepsy With Cataplexy JZP-258, Placebo - Narcolepsy With Cataplexy	Phase 3	Completed	Jazz Pharmaceuticals	201	2017-03-14	2020-11-12
Efficacy and Safety of Pitolisant in Pediatric Narcoleptic Patients With or Without Cataplexy, Double-blind Study Followed by a Prolonged Open-label Period pitolisant, Placebo - Narcolepsy With Cataplexy, Narcolepsy Without Cataplexy	Phase 3	Completed	Bioprojet	110	2016-06-06	2025-06-26
A Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With Cataplexy Xyrem - Narcolepsy With Cataplexy	Phase 3	Completed	Jazz Pharmaceuticals	106	2014-10-01	2019-04-30
Pitolisant to Assess Weekly Frequency of Cataplexy Attacks and EDS in Narcoleptic Patients (HARMONY CTP) Pitolisant, Placebo - Narcolepsy With Cataplexy, Excessive Daytime Sleepiness	Phase 3	Completed	Bioprojet	103	2013-04-01	2016-08-31

Narrower conditions

Narcolepsy (4)  ·  Cataplexy (1)  ·  Disorders of Excessive Somnolence (1)  ·  Sleep Wake Disorders (1)

Broader conditions

Dyssomnias (4)  ·  Mental Disorders (4)  ·  Nervous System Diseases (4)  ·  Sleep Disorders, Intrinsic (4)  ·  Disorders of Excessive Somnolence (3)  ·  Sleep Wake Disorders (3)  ·  Neurologic Manifestations (1)  ·  Pathological Conditions, Signs and Symptoms (1)  ·  Signs and Symptoms (1)

Interventions

Sodium Oxybate (2)  ·  pitolisant (2)

Sponsors

Bioprojet (2)  ·  Jazz Pharmaceuticals (2)

Countries

France (3)  ·  Finland (2)  ·  Italy (2)  ·  Netherlands (2)  ·  United States (2)  ·  Belgium (1)  ·  Czechia (1)  ·  Hungary (1)  ·  Russia (1)  ·  Spain (1)

Top investigators

Evelyne De Paillette, Dr (1)  ·  Giuseppe Plazzi, MD (1)

Results publications

PMID 28129985, PMID 30169321, PMID 33184650, PMID 34822113, PMID 34920345, PMID 34935103, PMID 35635687, PMID 35689598, PMID 36931805, PMID 36947322, PMID 37942930

NIH funding

2016 (1)