3 recruiting, 2 unknown. 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 1 | Recruiting 1 |
Follow Monogenic Obesity: new trials by email Literature Review of Monogenic Obesity trials Research Report on Monogenic Obesity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults Mibavademab - Monogenic Obesity | Phase 3 | Recruiting | Regeneron Pharmaceuticals | 4 | 2026-02-09 | 2026-10-22 |
| Efficacy of Semaglutide s.c. Once-weekly on Weight Loss and Management in Adolescents With Monogenic Obesity in Clinical Practice Semaglutide (administered by PDS290 pen-injector) - Monogenic Obesity | Recruiting | Prof. Dr. Martin Wabitsch | 70 | 2025-12-01 | 2026-01-08 | |
| A Multicenter Pharmacoepidemiological Cohort on Real Life Use of Semaglutide in Adolescents or Adults With Monogenic Obesity Monogenic Obesity | Recruiting | Assistance Publique - Hôpitaux de Paris | 175 | 2024-09-19 | 2026-06-24 | |
| Genetic Research of Monogenic Obesity in a Pediatric Cohort With Severe and Early Onset Obesity (GENOBE) monogenic obesity - Monogenic Obesity, Non Syndromic Obesity | Unknown | University Hospital, Bordeaux | 200 | 2024-02-01 | 2023-11-02 | |
| Genetic Research of Monogenic Obesity in a Pediatric Cohort With Severe and Early Onset Obesity Salivary Sampling - Monogenic Obesity | Unknown | University Hospital, Bordeaux | 100 | 2022-10-01 | 2022-05-05 |
Genetic Diseases, Inborn (1) · Obesity, Morbid (1)
Body Weight (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Nutrition Disorders (1) · Nutritional and Metabolic Diseases (1) · Obesity (1) · Overnutrition (1) · Overweight (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
semaglutide (1)
University Hospital, Bordeaux (2) · Assistance Publique - Hôpitaux de Paris (1) · Prof. Dr. Martin Wabitsch (1) · Regeneron Pharmaceuticals (1)
France (4) · Germany (2) · Netherlands (1) · Spain (1) · Turkey (Türkiye) (1) · United Kingdom (1)