6 unknown. 6 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Unknown 6 |
| Phase 2 | 4 | Unknown 4 |
Follow Keratoconus: new trials by email Literature Review of Keratoconus trials Research Report on Keratoconus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus NXL Energy 1, NXL Energy 2, NXL Energy 3 - Progressive Keratoconus | Phase 1 / Phase 2 | Unknown | Glaukos Corporation | 150 | 2022-03-08 | 2024-07-08 |
| Safety and Effectiveness of the PXL-Platinum 330 System PXL-330 Platinum device for crosslinking with Peschke riboflavin solution - Corneal Ectasia, Keratoconus | Phase 1 / Phase 2 | Unknown | Colorado Eye Consultants/Cornea Consultants of Colorado | 300 | 2020-06-01 | 2022-01-25 |
| Adapted Fluence Settings for Corneal Collagen Cross-linking in Mild to Moderate Progressive Keratoconus adjusted corneal collagen cross-linking, accelerated corneal collagen cross-linking, riboflavin 0.1% combined with dextran 20 % - Keratoconus | Phase 1 / Phase 2 | Unknown | Tehran University of Medical Sciences | 40 | 2014-08-01 | 2015-07-23 |
| Study of the Safety and Effectiveness of Collagen Cross-Linking at an Irradiance of 9 mW/cm2 and 18 mW/cm2 Riboflavin 0.1% ophthalmic solution, CCL-VARIO UV lamp, CCL-VARIO at 18 mW/cm2 - Keratoconus, Corneal Ectasia | Phase 1 | Unknown | Robert Mack, M.D. | 100 | 2013-10-01 | 2015-12-14 |
| Clinical and Structural Outcome of Conventional Versus Accelerated Corneal Collagen Cross-linking (CXL). UV-X 1000 (3 mW/cm²), UV-X 2000 (9 mW/cm²), riboflavin with hydroxypropyl methylcellulose - Keratoconus, Corneal Ectasia | Phase 1 / Phase 2 | Unknown | Oslo University Hospital | 40 | 2012-08-01 | 2016-08-30 |
| Outcomes in a Comparison of Manual Penetrating Keratoplasty and the IntraLase® Enabled Keratoplasty Penetrating keratoplasty with IntraLase, Penetrating keratoplasty with vacuum trephine - Keratoconus | Phase 1 | Unknown | Hospital Oftalmologico de Sorocaba | 60 | 2007-08-01 | 2007-12-03 |
Corneal Diseases (6) · Eye Diseases (6) · Pathological Conditions, Anatomical (1) · Pathological Conditions, Signs and Symptoms (1)
Riboflavin (3) · Chromatin Immunoprecipitation Sequencing (1) · Corneal Cross-Linking (1) · Hypromellose Derivatives (1) · Keratoplasty, Penetrating (1) · Ophthalmic Solutions (1) · Radiation (1) · Radiotherapy (1) · Subgingival Curettage (1)
Colorado Eye Consultants/Cornea Consultants of Colorado (1) · Glaukos Corporation (1) · Hospital Oftalmologico de Sorocaba (1) · Oslo University Hospital (1) · Robert Mack, M.D. (1) · Tehran University of Medical Sciences (1)
United States (3) · Brazil (1) · Iran (1)
Elissandro M Silva, Lindoso (1) · Fateme Alipour, MD (1) · Robert J Mack, M.D. (1) · S. Lance Forstot, M.D. (1)