6 completed, 1 not yet recruiting, 1 recruiting. 3 Phase 2, 2 Phase 1, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Echovirus Infections: new trials by email Literature Review of Echovirus Infections trials Research Report on Echovirus Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Protective Efficacy , Immunogenicity and Safety of the Tetravalent Inactivated Enterovirus Vaccine (Vero Cell). Tetravalent Inactivated Enterovirus Vaccine (Vero Cell), Placebo - Hand, Foot, and Mouth Disease(HFMD), Herpangina | Phase 3 | Not yet recruiting | Sinovac Biotech Co., Ltd | 6000 | 2026-05-01 | 2026-05-28 |
| Tolerability, Safety, and Immunogenicity of Tetravalent Inactivated Enterovirus Vaccine (Vero Cell). Low-dose of tetravalent inactivated enterovirus vaccine (Vero cell), Medium-dose tetravalent inactivated enterovirus vaccine (Vero cell), High-dose tetravalent inactivated enterovirus vaccine (Vero cell) ) - Hand, Foot, and Mouth Disease (HFMD), Herpangina | Phase 1 / Phase 2 | Completed | Sinovac Biotech Co., Ltd | 552 | 2025-01-15 | 2026-03-04 |
| Inactivated Bivalent Enterovirus Vaccine (Vero Cell) Phase I/II Clinical Trial low dose Bivalent Enterovirus Vaccine (Vero Cell), Inactivated, medium dose Bivalent Enterovirus Vaccine (Vero Cell), Inactivated, high dose Bivalent Enterovirus Vaccine (Vero Cell), Inactivated - Hand, Foot and Mouth Disease, Herpangina | Phase 1 / Phase 2 | Completed | Sinovac Biotech Co., Ltd | 744 | 2023-09-20 | 2026-06-26 |
| Surveillance of HFMD in Pediatric Outpatients Throat/buccal swab sample - Hand, Foot and Mouth Disease, Herpangina | Recruiting | University Hospital, Clermont-Ferrand | 3000 | 2023-06-20 | 2024-02-16 | |
| Sucralfate to Improve Oral Intake in Children With Infectious Oral Ulcers: a Randomized, Double-blind, Placebo-Controlled Trial Sucralfate, Placebo, Acetaminophen - Herpangina, Gingivostomatitis | Phase 2 | Completed | University of Texas at Austin | 102 | 2017-09-12 | 2021-10-29 |
| Effect of Recombinant Human Interferon α-2b Spray on Herpangina Recombinant Human Interferon α-2b Spray, Ribavirin - Herpangina | Phase 4 | Completed | Children's Hospital of Fudan University | 668 | 2016-06-01 | 2019-03-07 |
| Neurodevelopment Outcomes Following Severe Hand Foot and Mouth Disease in Vietnam Hand Foot and Mouth Disease | Completed | Oxford University Clinical Research Unit, Vietnam | 243 | 2013-06-01 | 2016-10-04 | |
| A Clinical Trial to Assess the Efficacy and Safety of an Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children Aged 6-35 Months inactivated vaccine (Vero Cell) against EV71, 0/0.5ml placebo - Hand, Foot and Mouth Disease, Herpangina | Phase 3 | Completed | Jiangsu Province Centers for Disease Control and Prevention | 10245 | 2012-01-01 | 2013-03-29 |
Herpangina (8) · Hand, Foot and Mouth Disease (7) · Enterovirus Infections (2) · Coxsackievirus Infections (1)
Infections (8) · Picornaviridae Infections (8) · RNA Virus Infections (8) · Virus Diseases (8) · Coxsackievirus Infections (7) · Enterovirus Infections (6)
Acetaminophen (1) · Ibuprofen (1) · Ribavirin (1) · Sucralfate (1) · Vaccines, Inactivated (1)
Sinovac Biotech Co., Ltd (3) · Children's Hospital of Fudan University (1) · Jiangsu Province Centers for Disease Control and Prevention (1) · Oxford University Clinical Research Unit, Vietnam (1) · University Hospital, Clermont-Ferrand (1) · University of Texas at Austin (1)
China (5) · France (1) · United States (1) · Vietnam (1)
Feng-Cai Zhu, Master (1) · Nina Vaidya, MD (1) · Saraswathy Sabanathan, MRCPCH (1) · Wang Shenyu, Dr. (1) · Yanxia Wang (1) · Zheng Yan (1)