5 recruiting, 4 completed, 2 unknown, 1 not yet recruiting. 8 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Recruiting 5, Completed 2, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Cervical Precancer: new trials by email Literature Review of Cervical Precancer trials Research Report on Cervical Precancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| C-3002: Enhancing Cervical Cancer Screening Access and Follow-up Care at 'CASCADE' Clinical Sites in the United States Qualitative interviews, Focus groups - Human Immunodeficiency Virus (HIV), Human Papillomavirus (HPV) | Not yet recruiting | UNC Lineberger Comprehensive Cancer Center | 3500 | 2026-11-10 | 2026-10-20 | |
| Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive Women Living With HIV in C1001P-CS7 Zimbabwe Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes - HIV (Human Immunodeficiency Virus), HPV | Not applicable | Recruiting | Fred Hutchinson Cancer Center | 300 | 2026-10-15 | 2026-10-19 |
| Feasibility Study Comparing One vs Two Probes for TA Among Cervical Cancer Screen Positive WLWH in C1001P-CS5 Rwanda Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes - HIV (Human Immunodeficiency Virus), HPV | Not applicable | Recruiting | Fred Hutchinson Cancer Center | 300 | 2026-10-15 | 2026-10-19 |
| Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive WLWH in C1001P-CS9 South Africa Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes - HIV (Human Immunodeficiency Virus), HPV | Not applicable | Recruiting | Fred Hutchinson Cancer Center | 200 | 2026-10-15 | 2026-10-20 |
| Feasibility Study Comparing Use of One Or Two Probes for Thermal Ablation Among Screen Positive Women Living With HIV in C1001P-CS2 Kenya Thermal ablation (TA) with 1 probe, Thermal ablation (TA) with 2 probes - HIV (Human Immunodeficiency Virus), HPV | Not applicable | Recruiting | Fred Hutchinson Cancer Center | 300 | 2026-10-12 | 2026-10-20 |
| Point of Care - Triage and Treatment for Cervical Pre-cancer IRIS™ Thermal Ablation Device - Cervical Precancer, Cervical Intraepithelial Neoplasia | Not applicable | Recruiting | Basic Health International, Inc. | 5000 | 2026-01-01 | 2026-08-28 |
| Feasibility of Intravaginal Artesunate as Adjuvant HPV & Cervical Precancer Treatment in Kenya Artesunate vaginal inserts, Placebo vaginal inserts - Human Immunodeficiency Virus, Human Papillomavirus | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 120 | 2025-01-22 | 2026-05-14 |
| Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya Artesunate pessary, Colposcopy - Cervix Cancer, Cervix Neoplasm | Phase 1 | Completed | UNC Lineberger Comprehensive Cancer Center | 17 | 2024-03-04 | 2025-08-19 |
| Development, Field Testing and Evaluation of the Efficacy of a Hand-held, Portable and Affordable Thermo-coagulator to Prevent Cervical Cancer in Low- and Middle-income Countries Thermocoagulation (device), Cryotherapy (device), LEEP (device) - Cervical Precancer | Not applicable | Completed | International Agency for Research on Cancer | 3124 | 2017-08-01 | 2024-07-08 |
| The Application of Invivo Microscopy Imaging in the Early Diagnosis of Cervical Cancer invivo microscopy group, normal group - Cervical Cancer, Cervical Precancer | Not applicable | Unknown | Shanghai First Maternity and Infant Hospital | 600 | 2016-12-01 | 2016-11-04 |
| Adherence to Preventive Care for Cervical Cancer Cervical Cancer, Cervical Precancer | Unknown | Brookdale University Hospital Medical Center | 400 | 2015-04-01 | 2015-04-10 | |
| Cervical Cancer Screening in Madagascar Using Smartphone Photos and Mobile Telemedicine D-VIA - Cervical Precancer | Not applicable | Completed | Prof. Patrick Petignat | 1041 | 2015-02-01 | 2016-02-26 |
Uterine Cervical Dysplasia (12) · Acquired Immunodeficiency Syndrome (6) · Uterine Cervical Neoplasms (6) · Neoplasms (1) · Papillomavirus Infections (1) · Precancerous Conditions (1)
Female Urogenital Diseases (12) · Female Urogenital Diseases and Pregnancy Complications (12) · Genital Diseases (12) · Genital Diseases, Female (12) · Urogenital Diseases (12) · Uterine Cervical Diseases (12) · Uterine Diseases (12) · Neoplasms (11) · Precancerous Conditions (11) · Communicable Diseases (7) · Infections (7) · Sexually Transmitted Diseases (7) · Sexually Transmitted Diseases, Viral (7) · Virus Diseases (7) · Blood-Borne Infections (6)
Colposcopy (1) · Cryotherapy (1) · Electrocoagulation (1) · Focus Groups (1)
Fred Hutchinson Cancer Center (4) · UNC Lineberger Comprehensive Cancer Center (3) · Basic Health International, Inc. (1) · Brookdale University Hospital Medical Center (1) · International Agency for Research on Cancer (1) · Prof. Patrick Petignat (1) · Shanghai First Maternity and Infant Hospital (1)
Kenya (3) · United States (2) · El Salvador (1) · Madagascar (1) · Rwanda (1) · South Africa (1) · Zambia (1) · Zimbabwe (1)
Leeya Pinder, MD, MPH (4) · Margaret M Madeleine, PhD, MPH (4) · Rachel L Winer, PhD, MPH (4) · Anandi Sheth, MD, MSc (1) · Chemtai Mungo, MD, MPH (1) · Chemtai Mungo, MD, MPH, FACOG (1) · Clement S Adebamowo, ScD (1) · Gregory Taylor, MD (1) · Jennifer S Smith, PhD (1) · Karla Alfaro, MD (1) · Katie Mollan, PhD (1) · Kayla Denson (1) · Laura Gaydos, PhD (1) · Lisa Flowers, MD, MPH (1) · Lisa Rahangdale, MD, MPH (1)
PMID 40907021, PMID 41415498, PMID 42403515
U24CA275417 (5), UG1CA275402 (4), 5UG1CA284671-03 (1), 5UG1CA284918-03 (1), R01CA285369 (1), R34CA284983 (1), UG1CA275400 (1), UG1CA275403 (1), UG1CA284883 (1), UG1CA284884 (1)