3 recruiting, 3 terminated, 2 active not recruiting. 6 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Active not recruiting 2, Recruiting 2, Terminated 2 |
| Phase 1 | 1 | Terminated 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Castration-Sensitive Prostate Carcinoma: new trials by email Literature Review of Castration-Sensitive Prostate Carcinoma trials Research Report on Castration-Sensitive Prostate Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial Androgen Therapy, Apalutamide, Docetaxel - Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Adenocarcinoma | Phase 3 | Recruiting | Alliance for Clinical Trials in Oncology | 1260 | 2025-12-01 | 2026-10-02 |
| FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial Antiandrogen Therapy, Bone Scan, Computed Tomography - Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 2 | Recruiting | Northwestern University | 125 | 2024-02-18 | 2026-10-08 |
| Vudalimab (XmAb20717) in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate Cancer Abiraterone, Biospecimen Collection, Bone Scan - Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Adenocarcinoma | Phase 1 | Terminated | Emory University | 4 | 2023-08-03 | 2025-09-15 |
| Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM) Pharmacotherapy Discontinuation, Follow-Up, Questionnaire Administration - Castration-Sensitive Prostate Carcinoma, Stage IV Prostate Cancer AJCC v8 | Phase 2 | Active not recruiting | Alliance for Clinical Trials in Oncology | 79 | 2022-11-21 | 2026-09-24 |
| Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer Abiraterone Acetate, Bicalutamide, Degarelix - Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Adenocarcinoma | Phase 2 | Recruiting | City of Hope Medical Center | 70 | 2021-05-04 | 2026-01-28 |
| Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer Antiandrogen Therapy, Abiraterone Acetate, Prednisone - Castration-Sensitive Prostate Carcinoma, Metastatic Malignant Neoplasm in the Bone | Phase 2 | Terminated | University of Washington | 10 | 2020-06-29 | 2023-10-26 |
| Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer Abiraterone Acetate, Antiandrogen Therapy, Apalutamide - Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Carcinoma | Phase 2 | Active not recruiting | OHSU Knight Cancer Institute | 7 | 2020-05-11 | 2026-07-15 |
| Docetaxel or Abiraterone Acetate With ADT in Treating Patients With Metastatic Hormone Sensitive Prostate Cancer Abiraterone Acetate, Antiandrogen Therapy, Docetaxel - Castration-Sensitive Prostate Carcinoma, Metastatic Prostatic Adenocarcinoma | Phase 2 | Terminated | University of Utah | 1 | 2019-02-08 | 2020-06-25 |
Genital Diseases (8) · Genital Diseases, Male (8) · Genital Neoplasms, Male (8) · Male Urogenital Diseases (8) · Neoplasms (8) · Neoplasms by Site (8) · Prostatic Diseases (8) · Urogenital Diseases (8) · Urogenital Neoplasms (8)
Abiraterone Acetate (4) · Androgen Antagonists (4) · Prednisone (4) · Docetaxel (3) · deltacortene (3) · prednylidene (3) · Magnetic Resonance Spectroscopy (2) · Radiation (2) · Radiotherapy (2) · Specimen Handling (2) · apalutamide (2) · Cytotoxins (1) · Glutamate Carboxypeptidase II (1) · Goserelin (1) · Leuprolide (1)
Alliance for Clinical Trials in Oncology (2) · City of Hope Medical Center (1) · Emory University (1) · Northwestern University (1) · OHSU Knight Cancer Institute (1) · University of Utah (1) · University of Washington (1)
United States (8)
Atish D. Choudhury, MD, PhD (1) · Bassel Nazha, MD, MPH (1) · Benjamin Maughan, MD (1) · David VanderWeele, MD, PhD (1) · Jing Zeng (1) · Julie Graff, MD (1) · Tanya Dorff (1)
P30CA033572 (1), P30CA060553 (1), P30CA138292 (1), P50CA097186 (1), U10CA180821 (1)