5 completed. 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 5 |
Follow Carcinoid Syndrome: new trials by email Literature Review of Carcinoid Syndrome trials Research Report on Carcinoid Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid Syndrome Randomized: 40 mg Paltusotine, Randomized: 80 mg Paltusotine - Carcinoid Syndrome, Carcinoid | Phase 2 | Completed | Crinetics Pharmaceuticals Inc. | 36 | 2022-04-22 | 2026-03-19 |
| Evaluating an Amino Acid Based Medical Food w/ Diarrhea in Carcinoid Syndrome & Other NETs Amino Acid Based Medical Food/Drink - Neuroendocrine Tumors, Carcinoid Tumor of GI System | Phase 2 | Completed | Lowell Anthony, MD | 10 | 2018-12-06 | 2022-11-03 |
| AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm Carbon C 11 Alpha-methyltryptophan, Laboratory Biomarker Analysis, Positron Emission Tomography - Carcinoid Syndrome, Metastatic Nonfunctional Well Differentiated Neuroendocrine Neoplasm | Phase 2 | Completed | Barbara Ann Karmanos Cancer Institute | 4 | 2018-06-20 | 2025-04-10 |
| Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Telotristat etiprate - Carcinoid Syndrome | Phase 2 | Completed | Lexicon Pharmaceuticals | 15 | 2010-06-15 | 2019-03-15 |
| Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stable-Dose Octreotide Therapy Telotristat etiprate, Octreotide LAR Depot, Placebo - Carcinoid Syndrome | Phase 2 | Completed | Lexicon Pharmaceuticals | 23 | 2009-03-01 | 2018-12-26 |
Serotonin Syndrome (5) · Neuroendocrine Tumors (2) · Carcinoid Tumor (1) · Carcinoid Tumors, Intestinal (1) · Diarrhea (1)
Chemically-Induced Disorders (5) · Drug-Related Side Effects and Adverse Reactions (5) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Neoplasms, Germ Cell and Embryonal (2) · Neoplasms, Nerve Tissue (2) · Neuroectodermal Tumors (2) · Adenocarcinoma (1) · Carcinoma (1) · Neoplasms, Glandular and Epithelial (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1) · Signs and Symptoms, Digestive (1)
telotristat (3) · Magnetic Resonance Spectroscopy (1) · Random Allocation (1) · alpha-methyltryptophan (1) · telotristat ethyl (1)
Lexicon Pharmaceuticals (2) · Barbara Ann Karmanos Cancer Institute (1) · Crinetics Pharmaceuticals Inc. (1) · Lowell Anthony, MD (1)
United States (4) · Argentina (1) · Brazil (1) · Canada (1) · Germany (1) · Mexico (1) · Peru (1) · Poland (1) · United Kingdom (1)
Anthony Shields (1) · Lowell Anthony (1) · Pablo LaPuerta, MD (1) · Pablo Lapuerta, MD (1)
PMID 25012985, PMID 25636046, PMID 27041406
2009 (1), P30CA022453 (1)