Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic

NCT01081197 — Completed, 150 participants, Helse Nord-Trøndelag HF

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Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic. A Neglected Area

Registry	NCT01081197
Status	Completed
Study type	Observational
Enrollment	150 (Actual)
Sponsor	Helse Nord-Trøndelag HF (Other)
Conditions	HEART DISEASE, Liver Failure, DEPRESSIVE DISORDER, Alcoholic Neuropathy
Interventions	Psychiatric and somatic examinations and ,if clinical indicated, treatment (Other)
Dates	start 2010-03-01, primary completion 2012-12-01, completion 2013-05-01, first posted 2010-03-05, last updated 2021-11-09
Locations	1 site in Norway

-Summary

Alcohol abuse is associated with a variety of clinical diseases, but studies on prevalence of different somatic diseases among alcohol abusers are lacking. Studies on populations in an out-day patients' clinic are also lacking.

The investigators aim to study somatic health standard in an out-day patients' clinic population of alcohol abusers, with regard to prevalence of different kinds of somatic diseases, and how the interaction of somatic and psychiatric treatment can influence on patients quality of life. Clinical examination including blood samples and echocardiographic examinations in all participants, other additional examinations (as x-ray, CT or MRI if indicated by clinical findings).

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+Detailed description

Retrospective methods will be used to study former somatic disease, cross-section design to study present somatic disease and prospective design to study quality of life, psychiatric and somatic health after combination of psychiatric and somatic examinations and treatment.

+Arms and interventions

Arm	Type	Interventions	Description
Out-day patients' clinic		Other: Psychiatric and somatic examinations and ,if clinical indicated, treatment	Alcohol abusers referred to out-day patients' clinic which consent to participate in the study
Control			Control group for the cardiac arm of the study will be matched controls from the Nord-Trøndelag Health Study (HUNT)

Psychiatric and somatic examinations and ,if clinical indicated, treatment (Other): Patients referred to the clinic will be given optimal treatment for revealed psychiatric and/or somatic disease including conversational therapy, and if indicated therapeutic interventions with respect to any kind of disease.

+Outcome measures

Primary outcomes

Prevalence of different kinds of somatic disease [3 months after inclusion]: Prevalence of somatic disease at study attendance of any kind, specified for heart disease, gall- and liver disease, neuropathic disease.

Secondary outcomes

Prevalence of former somatic disease [3 months after inclusion]: Prevalence of former somatic disease investigated by anamnestic examination, search in patient journals and communication with the patients community health service.
Outcome of psychiatric and somatic treatment of alcohol abusers [1 year after stopped inclusion]: Quality of life and score of somatic and psychiatric health 1 year after inclusion

+Eligibility

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* Alcohol abusers reffered to the out-day patients' clinic at Dep. of Psychiatry, Levanger Hospital, Norway

Exclusion Criteria:

* Not consenting to participate
* Not able to consent

+Locations (1)

Facility	City	Country	Status
Levanger Hospital, Dep. of Psychiatry	Levanger	Norway

+Publications

Moss M, Parsons PE, Steinberg KP, Hudson LD, Guidot DM, Burnham EL, Eaton S, Cotsonis GA. Chronic alcohol abuse is associated with an increased incidence of acute respiratory distress syndrome and severity of multiple organ dysfunction in patients with septic shock. Crit Care Med. 2003 Mar;31(3):869-77. doi: 10.1097/01.CCM.0000055389.64497.11. PMID 12626999
Awtry EH, Philippides GJ. Alcoholic and cocaine-associated cardiomyopathies. Prog Cardiovasc Dis. 2010 Jan-Feb;52(4):289-99. doi: 10.1016/j.pcad.2009.11.004. PMID 20109599
Moss M, Burnham EL. Alcohol abuse in the critically ill patient. Lancet. 2006 Dec 23;368(9554):2231-42. doi: 10.1016/S0140-6736(06)69490-7. PMID 17189035
Results publication: Dalen E, Holmen J, Nordahl HM. Somatic health of patients at an outpatient clinic for substance abuse. Tidsskr Nor Laegeforen. 2015 Jan 27;135(2):127-31. doi: 10.4045/tidsskr.13.0801. eCollection 2015 Jan 27. English, Norwegian. PMID 25625990

+Investigators

Erling Dalen, MD, Principal investigator, Helse Nord-Trøndelag HF