Nephrology Papers of the Week

ROC curve analysis demonstrated the diagnostic capability of the studied proteins, indicating their clinical utility in the diagnosis of renal injury.

In the present study, a recombinant STI-penetratin (rSTIP) fusion protein was developed to investigate whether fusion with penetratin could alter the insecticidal activity of STI.

We conducted a hypothesis-generating computational study to identify molecular overlap between predicted 6PPD-Q activity and diabetic kidney disease (DKD).

However, in Germany, in-depth research on this topic remains limited. Therefore, this study aims to explore barriers and facilitators experienced by nephrologists in CKM delivery to derive measures for improving its implementation.

We evaluated AF and CKD-related mortality trends and disparities in the U.S. from 1999 to 2024.

Background: The comparative risk of AP associated with PCABs versus PPIs remains uncertain. Study: This retrospective cohort study analyzed data from the TriNetX database, which included adult patients who received a prescription for either PCAB or PPI between January 1, 2016, and August 1, 2025.

This study aimed to identify potential factors associated with cefoperazone/sulbactam-induced coagulopathy and to characterize the dynamic changes in coagulation parameters in affected patients. Methods This retrospective case-control study identified 228 patients with adverse drug reactions (ADRs) from a hospital database.

Here, we describe a non-dialysis method that exploits the non-specific binding properties of compounds to determine fraction unbound over a broad dynamic range of concentrations.

We investigated whether DDR1-mediated mechanosensation links arterial stiffness to vascular smooth muscle cell (SMC)-endothelial paracrine communication in CKD-related atherosclerosis.

We investigated the associations of baseline cognitive frailty and changes in cognitive frailty status with incident CKM multimorbidity. This cohort study included participants aged ≥ 45 years from the CHARLS (2011-2018).

In a prospective UK Biobank cohort ( = 438,748), we evaluated their joint associations with incidence and risks of all-cause mortality, cirrhosis, hepatocellular carcinoma (HCC), cardiovascular disease (CVD), chronic kidney disease (CKD), non-liver cancers, and obesity-related cancers across MASLD and sarcopenia-related abnormality status.

The ARCH trial found more major adverse cardiovascular events (MACE) with romosozumab than with alendronate, whereas the placebo-controlled FRAME trial found no signal.

We introduce an opportunity to better leverage the value added by patients, families, caregivers, communities, and other key healthcare system partners such as dietitians, pharmacists, social workers, counselors, and nurse coordinators.

We provide explicit bedside guidance for the situations that clinicians find most difficult, including suspected secondary MI, the observe zone, and troponin elevation without a dynamic pattern.

The aim of this study is to examine the association and possible impact of GLP-1RA on patients with AAA.

We analyzed adult CMI-coded hospitalizations undergoing endovascular or open revascularization in the 2006-2020 National Inpatient Sample.

This review summarizes key cardiovascular disease prevention studies presented at the 2026 European Society of Cardiology (ESC) Congress, highlighting new evidence in lipid management, cardiovascular risk assessment, blood pressure control, and vaccination.

Here, we report on the current variability in terminology, present an expert proposal for kidney endpoints with a research agenda and outline the future strategy for a Delphi consensus.