3 completed, 1 recruiting. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1/2 Study to Evaluate the Safety, PK and Efficacy of TNP-2092 Administered Via IA Injection in PJI Participants TNP-2092 for injection, Vancomycin Hydrochloride for Injection (IA), Vancomycin Hydrochloride for Injection (IV) - Periprosthetic Joint Infection (PJI) | Phase 1 / Phase 2 | Recruiting | TenNor Therapeutics Inc. | 33 | 2025-04-03 | 2026-10-19 |
| Drug-Drug Interactions Between TNP-2198 and Midazolam, Clarithromycin Midazolam, Clarithromycin, TNP-2198 - Helicobacter Pylori Infection | Phase 1 | Completed | TenNor Therapeutics Inc. | 32 | 2024-08-26 | 2024-10-24 |
| Phase 1, Single-Dose and Multiple-Dose Continuous Intravenous Infusions of TNP-2092 for Injection in Healthy Chinese Participants TNP-2092 for injection, placebo - Acute Bacterial Skin and Skin Structure Infection (ABSSSI), Prosthetic Joints Infection (PJI) | Phase 1 | Completed | TenNor Therapeutics Inc. | 32 | 2022-07-07 | 2024-05-01 |
| The Safety and Tolerability, Pharmacokinetics of TNP-2092 Capsules in Combination With Rabeprazole Sodium Enteric-coated Tablets TNP-2092 capsules, TNP-2092 capsules placebo, Rabeprazole sodium enteric-coated tablets - Helicobacter Pylori Infection | Phase 1 | Completed | TenNor Therapeutics Inc. | 20 | 2017-10-10 | 2024-04-01 |
TNP-2092 (3) · Injections (2) · Anti-Bacterial Agents (1) · Clarithromycin (1) · Midazolam (1) · Vancomycin (1)
China (4)
Xiaojiao Li (1)