4 active not recruiting, 1 recruiting. 5 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Active not recruiting 4, Recruiting 1 |
| Phase 2 | 4 | Active not recruiting 4 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease LY3962681, Placebo (aCSF) - Parkinson's Disease | Phase 1 | Recruiting | Prevail Therapeutics | 124 | 2024-08-27 | 2026-10-16 |
| A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED) LY3884961 - Gaucher Disease, Gaucher Disease, Type 1 | Phase 1 / Phase 2 | Active not recruiting | Prevail Therapeutics | 8 | 2022-12-20 | 2026-08-17 |
| Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE) LY3884961, Methylprednisolone, Sirolimus - Gaucher Disease, Type 2 | Phase 1 / Phase 2 | Active not recruiting | Prevail Therapeutics | 7 | 2021-06-29 | 2026-10-22 |
| Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN) LY3884963, Methylprednisolone, Optional Sirolimus - Frontotemporal Dementia | Phase 1 / Phase 2 | Active not recruiting | Prevail Therapeutics | 35 | 2020-11-09 | 2026-07-16 |
| Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL) LY3884961, Methylprednisolone, Sirolimus - Parkinson Disease | Phase 1 / Phase 2 | Active not recruiting | Prevail Therapeutics | 32 | 2020-01-03 | 2026-10-13 |
Gaucher Disease (3) · Parkinson Disease (2) · Frontotemporal Dementia (1)
Methylprednisolone (3) · Sirolimus (2) · Prednisone (1)
United States (5) · United Kingdom (3) · Australia (2) · Germany (2) · Spain (2) · Belgium (1) · France (1) · Israel (1) · Japan (1) · Netherlands (1)
Aaron Tward, MD, PhD (1) · Hamzeh Migdadi, M.D. (1) · Travis B. Lewis, MD, PhD (1) · Travis Lewis (1) · Travis Lewis, MD, PhD (1)