3 completed, 2 terminated, 2 unknown, 1 recruiting. 5 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 2, Unknown 2, Recruiting 1 |
| Phase 2 | 3 | Terminated 2, Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309 PMC-309 monotherapy, PMC-309 Dose Escalation in Combination with Pembrolizumab(KEYTRUDA®), PMC-309 Dose Expansion - Advanced or Metastatic Solid Tumors | Phase 1 | Recruiting | PharmAbcine | 67 | 2024-01-03 | 2025-12-30 |
| Study to Assess Safety and Tolerability of PMC-403 in Subjects With Neovascular Age-related Macular Degeneration PMC-403 - Neovascular Age-related Macular Degeneration | Phase 1 | Completed | PharmAbcine | 17 | 2023-07-20 | 2025-12-30 |
| Olinvacimab With Pembrolizumab in Patients With mTNBC Olinvacimab - Metastatic Triple-Negative Breast Cancer | Phase 2 | Terminated | PharmAbcine | 19 | 2021-09-30 | 2025-12-30 |
| TTAC-0001 Phase II Trial With Recurrent Glioblastoma Progressed on Bevacizumab TTAC-0001 - Recurrent Glioblastoma | Phase 2 | Terminated | PharmAbcine | 19 | 2019-11-13 | 2022-08-18 |
| TTAC-0001 and Pembrolizumab Combination phase1b Trial in Recurrent Glioblastoma TTAC-0001 and pembrolizumab combination - Recurrent Glioblastoma | Phase 1 | Unknown | PharmAbcine | 9 | 2019-01-16 | 2022-08-17 |
| TTAC-0001 and Pembrolizumab Phase Ib Combination Trial in Metastatic Triple-negative Breast Cancer TTAC-0001 and pembrolizumab combination - Triple Negative Breast Cancer | Phase 1 | Unknown | PharmAbcine | 11 | 2019-01-03 | 2022-08-17 |
| Trial to Evaluate the Safety of TTAC-0001(Tanibirumab) in Recurrent Glioblastoma TTAC-0001 - Recurrent Glioblastoma | Phase 2 | Completed | PharmAbcine | 12 | 2016-02-04 | 2021-01-27 |
| Phase I Trial of Tanibirumab in Advanced or Metastatic Cancer Tanibirumab - Advanced Cancer, Metastatic Cancer | Phase 1 | Completed | PharmAbcine | 26 | 2011-11-01 | 2014-01-29 |
Glioblastoma (3) · Triple Negative Breast Neoplasms (2) · Neoplasm Metastasis (1)
olinvacimab (6) · Combined Modality Therapy (1) · pembrolizumab (1)
Australia (5) · South Korea (2) · United States (1)
Andrea Tazbirkova, Dr (1) · Brenton Seidl, Ph.D, MD (1) · Claire Beecroft, Ph.D, MD (1) · Daphne Day, Ph.D, MD (1) · Dhanusha Sabanathan, Ph.D, MD (1) · SeJoon Woo (1) · Young Seok Park, MD, PhD (1)